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Management of Castration Resistant Prostate Cancer
This volume provides new data about the molecular biology of CRPC and a review of the definition, staging and prognostic factors that define CRPC. The book features an in-depth review of proven therapeutic options, including bone-targeted therapies, immunotherapy, chemotherapy and hormonal based the...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor Corporativo: | |
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York, NY :
Springer New York : Imprint: Humana,
2014.
|
| Edición: | 1st ed. 2014. |
| Colección: | Current Clinical Urology,
|
| Temas: | |
| Acceso en línea: | Texto Completo |
MARC
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| 020 | |a 9781493911769 |9 978-1-4939-1176-9 | ||
| 024 | 7 | |a 10.1007/978-1-4939-1176-9 |2 doi | |
| 050 | 4 | |a RC870-923.2 | |
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| 245 | 1 | 0 | |a Management of Castration Resistant Prostate Cancer |h [electronic resource] / |c edited by Fred Saad, Mario A. Eisenberger. |
| 250 | |a 1st ed. 2014. | ||
| 264 | 1 | |a New York, NY : |b Springer New York : |b Imprint: Humana, |c 2014. | |
| 300 | |a XVI, 337 p. |b online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
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| 490 | 1 | |a Current Clinical Urology, |x 2197-7208 | |
| 505 | 0 | |a Introduction - Castration Resistant Prostate Cancer: A Rapidly Expanding Clinical State and a Model for New Therapeutic Opportunities -- Evolution of Clinical States and the Castration Resistant Clinical Paradigm -- Molecular Mechanisms of Prostate Cancer Progression after Castration -- New Imaging Modalities -- Androgen Receptor Biology in Castration Resistant Prostate Cancer -- The Androgen Receptor as a Therapeutic Target for Castration-Resistant Prostate Cancer -- Approaches Targeting Androgen Synthesis (CYP 17 inhibitors) -- Cytotoxic Chemotherapy (Taxanes and Taxane Combinations) -- The Emerging Role of Immunotherapy in Castrate Resistant Prostate Cancer -- Bone Targeted Therapy: Rationale and Current Status -- Radium-223 and Other Radiopharmaceuticals in Prostate Cancer -- Introduction -- Phase I/II targeted treatments -- Defining Clinical Endpoints in Castration-resistant Prostate Cancer -- Angiogenesis Inhibition in Castration Resistant Prostate Cancer -- Co-targeting Adaptive Survival Pathways -- Targeting the PI3K/AKT/mTOR Pathway in Prostate Cancer -- PARP Inhibitors -- Targeting C-Met/VEGF in Castration Resistant Prostate Cancer -- Epigenetics in Castration Resistant Prostate Cancer -- Undifferentiated Prostate Cancer and the Neuroendocrine Phenotype -- Strategies Addressing Quality of Life: Patient Reported Outcome and Symptoms Management -- Evidence-Based Therapeutic Approaches for mCRPC patients: Rational Sequence of Standard Treatment Options and Design for Future Drug Development. | |
| 520 | |a This volume provides new data about the molecular biology of CRPC and a review of the definition, staging and prognostic factors that define CRPC. The book features an in-depth review of proven therapeutic options, including bone-targeted therapies, immunotherapy, chemotherapy and hormonal based therapies. Combination therapy as well as novel targeted approaches presently under investigation are also reviewed. The text provides up-to-date guidelines and algorithms for the management of CRPC based on international guidelines presently available as well as evidence-based medicine. As a concise yet comprehensive summary of the current status of the field, Management of Castration Resistant Prostate Cancer serves as a very useful resource for physicians and researchers dealing with this challenging malignancy. | ||
| 650 | 0 | |a Urology. | |
| 650 | 0 | |a Oncology. | |
| 650 | 0 | |a Interventional radiology. | |
| 650 | 1 | 4 | |a Urology. |
| 650 | 2 | 4 | |a Oncology. |
| 650 | 2 | 4 | |a Interventional Radiology. |
| 700 | 1 | |a Saad, Fred. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 700 | 1 | |a Eisenberger, Mario A. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
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| 830 | 0 | |a Current Clinical Urology, |x 2197-7208 | |
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