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The Molecular Chaperones Interaction Networks in Protein Folding and Degradation

Molecular chaperones are a fundamental group of proteins that have been identified only relatively recently. They are key components of a protein quality machinery in the cell which insures that the folding process of any newly-synthesized polypeptide chain results in the formation of a properly fol...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Houry, Walid A. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2014.
Edición:1st ed. 2014.
Colección:Interactomics and Systems Biology ; 1
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Part I: Global View of the Chaperone Network
  • Analysis of Chaperone Network Throughput
  • Part II: Chaperones at the Ribosome
  • Functions of Ribosome-associated Chaperones and Their Interaction Network
  • Part III: The Hsp 70 and Hsp40 Chaperone Networks
  • Yeast Hsp70 and J-protein Chaperones: Function and Interaction Network
  • The Chaperone Networks: An Hsp70 Perspective
  • Part IV: The Hsp90 Chaperone Network
  • The Interaction Network of the Hsp90 Molecular Chaperone
  • A Global View of the Proteome Perturbations by Hsp90 Inhibitors
  • Designing Drugs Against Hsp90 for Cancer Therapy
  • The Candida albicans Hsp90 Chaperone Network is Environmentally Flexible and Evolutionarily Divergent
  • Part V: The p23 Chaperone Network
  • Emergence and Characterization of the p23 Molecular Chaperone
  • Part VI: Chaperones in the ER: Function and Interaction Network
  • Chaperones of the ERAD Pathway
  • Chaperones and Proteases of Mitochondria: From Protein Folding and Degradation to Mitophagy
  • Part VII: The Ubiquitin-Proteasome System Network
  • The Biogenesis of the Eukaryotic Proteasome
  • Systems-wide Analysis of Protein Ubiquitylation: We Finally Have the Tiger by the Tail
  • Part VIII: The Chaperone and Protease Networks in Model Bacteria and Parasites
  • The Interaction Networks of E. coli Chaperones
  • Chaperone-Proteases of Mycobacteria
  • The Interaction Networks of Hsp70 and Hsp90 in the Plasmodium and Leishmania Parasites
  • Index. .