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Post-Traumatic Arthritis Pathogenesis, Diagnosis and Management /

Bringing together the most up-to-date research on post-traumatic arthritis (PTA) and its management, this book is a comprehensive presentation of the current thinking on all aspects of the mechanisms of joint injury and subsequent development of PTA. Divided into thematic sections, it includes discu...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Olson, MD, Steven A. (Editor ), Guilak, PhD, Farshid (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer US : Imprint: Springer, 2015.
Edición:1st ed. 2015.
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Section I: The Problem of Post-Traumatic Arthritis
  • Arthritis that Develops after Joint Injury: Is it Post-Traumatic Arthritis or Post-Traumatic OsteoArthritis?
  • Post-Traumatic Arthritis: Definitions and Burden of Disease
  • Arthritis after Joint Injury: The Military Experience
  • Section II: Experimental Models of Joint Injury
  • In Vitro Cartilage Explant Injury Models
  • Animal Models of Meniscal Injury in Post-Traumatic Arthritis.-Anterior Cruciate Transection/Disruption Models of Posttraumatic Arthritis
  • Closed Joint ACL Disruption Murine Model of PTA
  • Whole Joint Models of Articular Injury and Articular Fracture
  • Instability: Dynamic Loading Models
  • Survey of Animal Models in Post-Traumatic Arthritis: Choosing the Right Model to Answer the Right Question
  • Section III: Peri-articular Tissue Response to Joint Injury
  • The Response of Cartilage to Injury
  • The Response of Subchondral Bone to Injury
  • Genetic Variability in the Response to Injury
  • Aging and Post-Traumatic Arthritis.-Potential Mechanisms of PTA: Cell Death
  • Potential Mechanisms of PTA: Inflammation
  • Potential Mechanisms of PTA: Oxidative Stress
  • Potential Mechanisms of PTA: Alterations in Joint Loading
  • Section IV: Clinical Assessment and Treatment of Patients with Joint Injury
  • Imaging Specific to Cartilage Injury
  • Outcomes of ACL Injury: The MOON Consortium
  • Current Treatment and Outcomes of Intra-articular Fractures
  • Non-arthroplasty Treatments for PTA in the Lower Extremity
  • Results of Arthroplasty in Post-Traumatic Arthritis
  • Section V: Developing and Future Assessment and Therapies
  • Measurement of Severity of Injury after Articular Fracture and Correlation with Post-Traumatic Arthritis Development
  • Biomarkers of PTA
  • Potential Targets for Pharmacologic Therapies for Prevention of PTA.- Stem Cells Therapies for Post-Traumatic Arthritis
  • Unanswered Questions and Future Directions.