Logic Synthesis for Genetic Diseases Modeling Disease Behavior Using Boolean Networks /

This book brings to bear a body of logic synthesis techniques, in order to contribute to the analysis and control of Boolean Networks (BN) for modeling genetic diseases such as cancer. The authors provide several VLSI logic techniques to model the genetic disease behavior as a BN, with powerful impl...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores principales: Lin, Pey-Chang Kent (Autor), Khatri, Sunil P. (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2014.
Edición:1st ed. 2014.
Temas:
Electronic circuits.
Biomedical engineering.
Bioinformatics.
Electronic Circuits and Systems.
Biomedical Engineering and Bioengineering.
Computational and Systems Biology.
Acceso en línea:Texto Completo

MARC

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100 1 |a Lin, Pey-Chang Kent.  |e author.  |4 aut  |4 http://id.loc.gov/vocabulary/relators/aut 
245 1 0 |a Logic Synthesis for Genetic Diseases  |h [electronic resource] :  |b Modeling Disease Behavior Using Boolean Networks /  |c by Pey-Chang Kent Lin, Sunil P. Khatri. 
250 |a 1st ed. 2014. 
264 1 |a New York, NY :  |b Springer New York :  |b Imprint: Springer,  |c 2014. 
300 |a XXI, 100 p. 28 illus., 8 illus. in color.  |b online resource. 
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505 0 |a Introduction -- Part I Inference of Gene Regulatory Networks -- Predictor Set Inference using SAT -- Determining Gene Function in Boolean Networks using SAT -- Predictor Ranking using Modified Zhegalkin Functions -- Part II Intervention of Gene Regulatory Networks -- ATPG for Cancer Therapy -- Summary and Future Work. 
520 |a This book brings to bear a body of logic synthesis techniques, in order to contribute to the analysis and control of Boolean Networks (BN) for modeling genetic diseases such as cancer. The authors provide several VLSI logic techniques to model the genetic disease behavior as a BN, with powerful implicit enumeration techniques. Coverage also includes techniques from VLSI testing to control a faulty BN, transforming its behavior to a healthy BN, potentially aiding in efforts to find the best candidates for treatment of genetic diseases.    • Discusses a new application for logic synthesis, which enables the use of Boolean Networks to model the behavior of genetic-based diseases; • Demonstrates how techniques such as Boolean Satisfiability (SAT) and Automatic Test Pattern Generation (ATPG) can be applied in the context of genetics; • Provides content that appeals to researchers in genetics and logic synthesis and enables readers to make the connection between genetic diseases and logic techniques in a clear, unambiguous manner. 
650 0 |a Electronic circuits. 
650 0 |a Biomedical engineering. 
650 0 |a Bioinformatics. 
650 1 4 |a Electronic Circuits and Systems. 
650 2 4 |a Biomedical Engineering and Bioengineering. 
650 2 4 |a Computational and Systems Biology. 
700 1 |a Khatri, Sunil P.  |e author.  |4 aut  |4 http://id.loc.gov/vocabulary/relators/aut 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer Nature eBook 
776 0 8 |i Printed edition:  |z 9781461494287 
776 0 8 |i Printed edition:  |z 9781461494300 
776 0 8 |i Printed edition:  |z 9781493955350 
856 4 0 |u https://doi.uam.elogim.com/10.1007/978-1-4614-9429-4  |z Texto Completo 
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912 |a ZDB-2-SXE 
950 |a Engineering (SpringerNature-11647) 
950 |a Engineering (R0) (SpringerNature-43712) 

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