Cargando…

The Toxicant Induction of Irritant Asthma, Rhinitis, and Related Conditions

Untoward reactions to environmental chemicals, particularly when a subject reports difficulties with exposures to chemicals of diverse classes involving more than one organ system, have been poorly understood and an area of great controversy. Studies of airway inflammation induced by respiratory irr...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Meggs, William J. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer US : Imprint: Springer, 2013.
Edición:1st ed. 2013.
Temas:
Acceso en línea:Texto Completo

MARC

LEADER 00000nam a22000005i 4500
001 978-1-4614-9044-9
003 DE-He213
005 20220113095214.0
007 cr nn 008mamaa
008 140123s2013 xxu| s |||| 0|eng d
020 |a 9781461490449  |9 978-1-4614-9044-9 
024 7 |a 10.1007/978-1-4614-9044-9  |2 doi 
050 4 |a RM300-666 
072 7 |a MMG  |2 bicssc 
072 7 |a MED071000  |2 bisacsh 
072 7 |a MKG  |2 thema 
082 0 4 |a 615  |2 23 
245 1 4 |a The Toxicant Induction of Irritant Asthma, Rhinitis, and Related Conditions  |h [electronic resource] /  |c edited by William J. Meggs. 
250 |a 1st ed. 2013. 
264 1 |a New York, NY :  |b Springer US :  |b Imprint: Springer,  |c 2013. 
300 |a VI, 294 p. 24 illus., 18 illus. in color.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
505 0 |a Introduction: Irritant asthma, irritant rhinitis -- Airway Anatomy, Physiology, and Inflammation -- Reactive Airways Dysfunction Syndrome (RADS) and Irritant-Induced Asthma -- Acute Toxicity of Respiratory Irritant Exposures -- Particulate Exposure and Cardiovascular Inflammation -- Products of Combustion -- Irritant and Airborne Contact Dermatitis -- Exposure Limits -- Occupational Issues Related to Respiratory Irritants -- The Brain as a Target Organ for Allergic and Irritant Sensitivity: A Review and Suggestions for Research -- An Approach to Treating Irritant Airway Inflammation -- Summary and Research Needs -- Index. 
520 |a Untoward reactions to environmental chemicals, particularly when a subject reports difficulties with exposures to chemicals of diverse classes involving more than one organ system, have been poorly understood and an area of great controversy. Studies of airway inflammation induced by respiratory irritants have established neurogenic inflammation as the mechanism for irritant asthma and rhinitis. Remodeling of the airway after an acute irritant exposure can lead to a heightened sensitivity to irritants that persists. Recognition that rhinitis, while sometimes regarded as a trivial disease, is associated with extra-airway manifestations such as fatigue and disturbances of sleep, mood, and cognition, further elucidates how chemical exposures can be serious for susceptible individuals. This book reviews current scientific understanding of irritant airway inflammation and related conditions, including cardiovascular effects of particulate exposures, airborne contact dermatitis and irritant dermatitis, and the brain as a target organ for both allergic and irritant reactions. It is essential reading for physicians and other healthcare workers caring for patients with environmental intolerances.  Allergists, toxicologists, occupational and environmental physicians, and pulmonologists will find the materials particularly valuable. Patients and advocates for those with chemical intolerances will also find the book of interest. 
650 0 |a Pharmacology. 
650 0 |a Medical sciences. 
650 0 |a Immunology. 
650 1 4 |a Pharmacology. 
650 2 4 |a Health Sciences. 
650 2 4 |a Immunology. 
700 1 |a Meggs, William J.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer Nature eBook 
776 0 8 |i Printed edition:  |z 9781461490456 
776 0 8 |i Printed edition:  |z 9781461490432 
776 0 8 |i Printed edition:  |z 9781489979490 
856 4 0 |u https://doi.uam.elogim.com/10.1007/978-1-4614-9044-9  |z Texto Completo 
912 |a ZDB-2-SBL 
912 |a ZDB-2-SXB 
950 |a Biomedical and Life Sciences (SpringerNature-11642) 
950 |a Biomedical and Life Sciences (R0) (SpringerNature-43708)