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Pharmaco-Imaging in Drug and Biologics Development Fundamentals and Applications /

Advances in drugs and biologics to mitigate or cure some of nature's most complex medical problems have been incredible to behold.  These accomplishments are due to the actions of a wide theatre of participants from biologists, pharmacologists, geneticists, chemists and manufacturers, molecular...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Moyer, Brian R. (Editor ), Cheruvu, Narayan P.S (Editor ), Hu, Tom C.-C (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2014.
Edición:1st ed. 2014.
Colección:AAPS Advances in the Pharmaceutical Sciences Series, 8
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Imaging Platforms and Drug Development:  An Introduction
  • Imaging in Drug Development: Animal Models, Handling and Physiological Constraints
  • Considerations for Pre-Clinical Laboratory Animal Imaging Center Design, Setup, and Management suitable for Biomedical Investigation for Drug Discovery
  • Pharmaco-Imaging in Translational Science and Research
  • The Role of Pharmacokinetics and Allometrics in Imaging: Practical Issues and Considerations
  • Quantitative Imaging Using Autoradiographic Techniques
  • Pre-Clinical Imaging in Oncology: Considerations and Recommendations for the Imaging Scientist
  • Use of Radiolabelled Leukocytes for Drug Evaluation in Man
  • Application of Bioluminescence Imaging (BLI) to the Study of the Animal Models of Human Infectious Diseases
  • Pre-Clinical Imaging in BSL-3 and BSL-4 Environments:  Imaging Pathophysiology of Highly Pathogenic Infectious Diseases
  • Magnetic Resonance as a Tool for Pharmaco-Imaging
  • Technologies and Principles of Mass Spectral Imaging
  • Regulatory Considerations Involved In Imaging.