Cargando…

Molecular Genetics of Axial Patterning, Growth and Disease in the Drosophila Eye

Undoubtedly, Drosophila melanogaster, fruit fly, has proven to be one of the most popular invertebrate model organisms, and the work horse for modern day biologists. Drosophila, a highly versatile model with a genetic legacy of more than a century, provides powerful genetic, cellular, biochemical an...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Singh, Amit (Editor ), Kango-Singh, Madhuri (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2013.
Edición:1st ed. 2013.
Temas:
Acceso en línea:Texto Completo

MARC

LEADER 00000nam a22000005i 4500
001 978-1-4614-8232-1
003 DE-He213
005 20220116230211.0
007 cr nn 008mamaa
008 130913s2013 xxu| s |||| 0|eng d
020 |a 9781461482321  |9 978-1-4614-8232-1 
024 7 |a 10.1007/978-1-4614-8232-1  |2 doi 
050 4 |a RB155-155.8 
072 7 |a MFN  |2 bicssc 
072 7 |a MED107000  |2 bisacsh 
072 7 |a MFN  |2 thema 
082 0 4 |a 616.042  |2 23 
245 1 0 |a Molecular Genetics of Axial Patterning, Growth and Disease in the Drosophila Eye  |h [electronic resource] /  |c edited by Amit Singh, Madhuri Kango-Singh. 
250 |a 1st ed. 2013. 
264 1 |a New York, NY :  |b Springer New York :  |b Imprint: Springer,  |c 2013. 
300 |a XIV, 368 p. 68 illus., 63 illus. in color.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
505 0 |a Early eye development: Specification and Determination -- Molecular genetic mechanisms of axial patterning: Mechanistic insights into generation of axes in the developing eye -- Catching the Next Wave: Patterning of the Drosophila Eye by the Morphogenetic Furrow -- Cell Morphogenesis -- Cell Polarity in Drosophila Retina -- Negative regulation for neural patterning in the Drosophila eye -- Cell Adhesion during Drosophila eye development -- Modulation of Developmental Signaling by the Proteostasis Network -- Drosophila eye as a model to study regulation of growth control: The discovery of size control pathways -- Contribution of the Drosophila eye to unraveling the basis of neurodegeneration -- Genetic regulation of early eye development in non-dipteran insects -- Development and evolution of the Drosophila Bolwig's organ: a compound eye relict -- Index. 
520 |a Undoubtedly, Drosophila melanogaster, fruit fly, has proven to be one of the most popular invertebrate model organisms, and the work horse for modern day biologists. Drosophila, a highly versatile model with a genetic legacy of more than a century, provides powerful genetic, cellular, biochemical and molecular biology tools to address many questions extending from basic biology to human diseases.  One of the most important questions in biology focuses on: how does a multi-cellular organism develop from a single-celled embryo? The discovery of the genes responsible for pattern formation has helped refine this question.  Drosophila eye model has been extensively used to study molecular genetic mechanisms involved in patterning and growth. Since the genetic machinery involved in the Drosophila eye is similar to humans, it has been used to model human diseases and homology to eyes in other taxa. This book will discuss molecular genetic mechanisms of pattern formation, axial patterning, growth regulation in Drosophila eye, and more. 
650 0 |a Medical genetics. 
650 0 |a Biology-Technique. 
650 0 |a Medicine-Research. 
650 0 |a Biology-Research. 
650 1 4 |a Medical Genetics. 
650 2 4 |a Experimental Organisms. 
650 2 4 |a Biomedical Research. 
700 1 |a Singh, Amit.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
700 1 |a Kango-Singh, Madhuri.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer Nature eBook 
776 0 8 |i Printed edition:  |z 9781461482338 
776 0 8 |i Printed edition:  |z 9781461482314 
776 0 8 |i Printed edition:  |z 9781493953035 
856 4 0 |u https://doi.uam.elogim.com/10.1007/978-1-4614-8232-1  |z Texto Completo 
912 |a ZDB-2-SBL 
912 |a ZDB-2-SXB 
950 |a Biomedical and Life Sciences (SpringerNature-11642) 
950 |a Biomedical and Life Sciences (R0) (SpringerNature-43708)