Advances in Chronic Lymphocytic Leukemia

Chronic lymphocytic leukemia (CLL) is the most common leukemia in the Western world. CLL has a highly varied clinical course.  While advances in CLL therapy are noted, many patients still succumb to this illness. Like most progress in medicine, solid advances in the diagnosis, prognosis and treatmen...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Malek, Sami (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2013.
Edición:1st ed. 2013.
Colección:Advances in Experimental Medicine and Biology, 792
Temas:
Cancer.
Cancer Biology.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Preface
  • B-cell receptor and antigens in CLL
  • The CLL cell microenvironment
  • Acquired genomic copy number aberrations in CLL
  • Recurrent gene mutations in CLL
  • TP53 aberrations in CLL
  • Gene expression and epigenetic deregulation
  • Apoptosis deregulation in CLL
  • Richter's Syndrome
  • Molecular biomarkers in chronic lymphocytic leukemia
  • Critical Signal Transduction Pathways in CLL
  • Immunotherapies in CLL
  • Novel therapeutic agents in CLL
  • Inherited susceptibility to CLL
  • miR deregulations in CLL
  • Index.

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