War in the Body The Evolutionary Arms Race Between HIV and the Human Immune System and the Implications for Vaccines /

In the relatively few decades since the introduction of HIV into the human population, variants of the virus have diverged to such an extent that, were the discussion about something other than viruses, said variants could easily be classified as different species. This book will consider these evol...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores principales: Wick, W David (Autor), Yang, Otto O. (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2013.
Edición:1st ed. 2013.
Temas:
Virology.
Immunology.
Pharmacology.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • The HIV Infection model
  • The CTL Model
  • Simulating an HIV Infection In Vivo
  • The Escape Formula
  • Early and Late Escapes
  • Understanding Escape
  • More Topics about Escape from Immune Control
  • HIV's Cloaking Device: The Fascinating Story of Nef
  • Retroviral Sex and Escape
  • The Ne Business Again and a Proposed Experiment
  • Can a T-cell Vaccine Block Escape?
  • The STEP Trial and the Future of T-cell Vaccines
  • Short Tutorial on Dynamical Models
  • Deterministic Modeling: A Cautionary Example
  • The Infection Model Defined
  • The CTL Model Defined
  • On Simulation Techniques
  • Derivation of the Escape Formula
  • Statistics of the Mutant Lineage in Classical Genetics
  • Extinction Probabilities with Extra Poisson Variation
  • Computing the Boundaries
  • Co-existence or Replacement?
  • The Nef-Deletion Threshold Formulas
  • Modeling Retroviral Sex.

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