MHC Class I Antigens In Malignant Cells Immune Escape And Response To Immunotherapy /

Abnormal expression of MHC class I molecules in malignant cells is a frequent occurrence that ranges from total loss of all class I antigens to partial loss of MHC specific haplotypes or alleles. Different mechanisms are described to be responsible for these alterations, requiring different therapeu...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores principales: Aptsiauri, Natalia (Autor), Garcia-Lora, Angel Miguel (Autor), Cabrera, Teresa (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2013.
Edición:1st ed. 2013.
Colección:SpringerBriefs in Cancer Research, 1
Temas:
Cancer.
Immunology.
Medicine-Research.
Biology-Research.
Cancer Biology.
Biomedical Research.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Overview of MHC Class I Antigens
  • HLA Class I Expression In Human Cancer
  • MHC Class I Expression In Experimental Mouse Models Of Cancer: Immunotherapy Of Tumors With Different MHC-I Expression Patterns
  • Potential Therapeutic Approaches For Increasing Tumor Immunogenicity By Upregulation Of Tumor HLA Class I Expression
  • Conclusion.

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