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Sequential Experimentation in Clinical Trials Design and Analysis /
This book presents an integrated methodology for sequential experimentation in clinical trials. The methodology allows sequential learning during the course of a trial to improve the efficiency of the trial design, which often lacks adequate information at the planning stage. Adaptation via sequenti...
| Clasificación: | Libro Electrónico |
|---|---|
| Autores principales: | , , |
| Autor Corporativo: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York, NY :
Springer New York : Imprint: Springer,
2013.
|
| Edición: | 1st ed. 2013. |
| Colección: | Springer Series in Statistics,
298 |
| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- Introduction
- Nonlinear Regression, Experimental Design, and Phase I Clinical Trials
- Sequential Testing Theory and Stochastic Optimization over Time
- Group Sequential Design of Phase II and III Trials
- Sequential Methods for Vaccine Safety Evaluation and Surveillance in Public Health
- Time-Sequential Design of Clinical Trials with Failure-Time Endpoints
- Confidence Intervals and p-Values
- Adaptive Design of Confirmatory Trials
- References.