DNA Helicases and DNA Motor Proteins

In recent years, a number of groundbreaking structural and mechanistic studies deepened our understanding of helicase mechanisms and established new approaches for their analyses. Many fundamental mechanistic questions ranging from the mechanism of force generation, mechanochemical coupling to disti...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Spies, Maria (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2013.
Edición:1st ed. 2013.
Colección:Advances in Experimental Medicine and Biology, 767
Temas:
Medical genetics.
Biochemistry.
Cytology.
Medicine-Research.
Biology-Research.
Medical Genetics.
Cell Biology.
Biomedical Research.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Preface
  • Overview: What are DNA helicases?
  • Structure and mechanisms of SF1 DNA helicases
  • Structure and mechanisms of SF2 DNA helicases
  • Structure and mechanisms of hexameric helicases
  • Helicases at the replication fork
  • DNA helicases associated with genetic instability, cancer and aging
  • The Helicase-primase complex as a target for effective herpesvirus antivirals
  • RecQ helicases - conserved guardians of genetic integrity
  • Roles of DNA helicases in the mediation and rRegulation of homologous recombination
  • DNA helicases in NER, BER and MMR
  • Roles for helicases as ATP-dependent molecular switches
  • The FtsK family of DNA pumps
  • ATP dependent chromatin remodelers
  • Index.

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