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RNA Interference from Biology to Therapeutics

The Nobel Prize winning discovery that small interfering RNA can be utilised to control cellular gene expression has propelled the field of RNA interference (RNAi) to the forefront of biomedical science as a potential molecular medicine set to revolutionalise disease treatment.   Harnessing the mole...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Howard, Kenneth A. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer US : Imprint: Springer, 2013.
Edición:1st ed. 2013.
Colección:Advances in Delivery Science and Technology,
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • RNA Interference Pathways and Therapeutic Exploitation RNA Interference
  • Synthetic Dicer-Substrate siRNAs as Triggers of RNA Interference
  • The Role of MicroRNAs in Natural Tissue Development and Application in Regenerative Medicine
  • Intracellular Delivery Considerations for RNAi Therapeutics
  • Mucosal Delivery of RNAi Therapeutics
  • Nanomedicines for Systemic Delivery of RNAi Therapeutics
  • Lipidoids: A Combinatorial Approach to siRNA Delivery
  • Polymeric Micelles for siRNA Delivery
  • RNAi Therapeutic Delivery by Exosomes
  • Aptamer-Mediated siRNA Targeting
  • RNAi as Anti-Viral Therapy: The HIV-1 Case
  • Genome-Wide RNAi Screen for Identification of Human Host Factors Crucial for Influenza Virus Replication
  • The Application of microRNAs in Cancer Diagnostics
  • Therapeutic Application of miRNAs in Cancer
  • Clinical Development of an Inhalable Anti-RSV siRNA Treatment.