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Complement Therapeutics
This book highlights progress and trends in the rapidly evolving field of complement-related drug discovery and spotlights examples of clinical applications. As an integral part of innate immunity and critical mediator in homeostatic and inflammatory processes, the human complement system has been i...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor Corporativo: | |
| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York, NY :
Springer US : Imprint: Springer,
2013.
|
| Edición: | 1st ed. 2013. |
| Colección: | Advances in Experimental Medicine and Biology,
735 |
| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- Progress and Trends in Complement Therapeutics
- Inhibition of the serine proteases of the complement system
- The role of MASP-1/3 in complement activation
- Membrane-bound complement regulatory proteins as biomarkers and potential therapeutic targets for SLE
- DAF as a therapeutic target for steroid hormones: implications for host pathogen interactions
- Targeting gC1qR domains for therapy against infection and inflammation
- The Alternative C5a Receptor Function
- The effects of selective complement- and CD14-inhibition on the E. coli-induced tissue factor mRNA up-regulation, monocyte tissue factor expression and tissue factor functional activity in human whole blood
- CR2-Mediated Targeting of Complement Inhibitors: Bench-to-Bedside Using a Novel Strategy for Site-Specific Complement Modulation
- Paroxysmal nocturnal hemoglobinuria and the complement system: recent insights and novel anti-complement strategies
- Defective Complement Action and Control Defines Disease Pathology for Retinal and Renal Disorders and Provides a Basis for new Therapeutic Approaches
- C3 Glomerulonephritis/CFHR5 Nephropathy is an endemic disease in Cyprus: Clinical and molecular findings in 21 families
- Complement-targeted therapeutics in periodontitis
- Complement system activation in cardiac and skeletal muscle pathology: Friend or foe?
- Innate immunity as orchestrator of bone marrow homing for hematopoietic stem/progenitor cells
- Complement-mediated microvascular injury leads to chronic rejection
- Targeting complement at the time of transplantation
- Evaluation of the blood compatibility of materials, cells and tissues: Basic concepts, test models and practical guidelines
- Non-invasive detection of complement activation through radiologic imaging
- Highly Multiplexed Proteomic Platform for Biomarker Discovery, Diagnostics and Therapeutics
- Complement in Action: A Review of Patent Trends From 1976 through 2011.