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NanoCellBiology of Secretion Imaging Its Cellular and Molecular Underpinnings /
Understanding live cells at the single molecule level is the most important and single major challenge facing biology and medicine today. Over the past 15 years, there has been a renewed understanding of living cells at the molecular level. Atomic Force Microscopy, Laser Force Microscopy, single sec...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Autor Corporativo: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York, NY :
Springer New York : Imprint: Springer,
2012.
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| Edición: | 1st ed. 2012. |
| Colección: | SpringerBriefs in Biological Imaging,
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| Temas: | |
| Acceso en línea: | Texto Completo |
MARC
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| 100 | 1 | |a Jena, Bhanu P. |e author. |4 aut |4 http://id.loc.gov/vocabulary/relators/aut | |
| 245 | 1 | 0 | |a NanoCellBiology of Secretion |h [electronic resource] : |b Imaging Its Cellular and Molecular Underpinnings / |c by Bhanu P. Jena. |
| 250 | |a 1st ed. 2012. | ||
| 264 | 1 | |a New York, NY : |b Springer New York : |b Imprint: Springer, |c 2012. | |
| 300 | |a XII, 70 p. 38 illus., 33 illus. in color. |b online resource. | ||
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| 490 | 1 | |a SpringerBriefs in Biological Imaging, |x 2193-3367 | |
| 505 | 0 | |a Understanding live cells at the single molecule level is the most important and single major challenge facing biology and medicine today. Over the past 15 years, there has been a renewed understanding of living cells at the molecular level. Atomic Force Microscopy, Laser Force Microscopy, single secretory vesicle patch clamp studies, highresolution electron microscopy, and x-ray diffraction, are some of the tools now being used to unravel the intricacies of a living cell at the molecular level. Opening with an explanation of Materials and Methods, NanoCellBiology then moves through discussions of porosome discovery, calcium and SNARE-induced fusion, and vesicle swelling before winding up in a final chapter of conclusions and future studies. Succinctly packaged as SpringerBrief, this book is a must for those studying or conducting research in cell biology, biochemistry or nanobiology/nanotechnology. This book will be invaluable to faculty & graduate students involved in Nano Courses; Cell Biology Courses; Biophysics Courses; and Biochemistry Courses as well as practicing Cell Biologists, Biochemists and BioPhysicists. Table of contetns: Introduction -- Materials & Methods -- Porosome Discovery -- Calcium & SNARE-Induced Membrane Fusion -- SNAREs need to reside in opposing membrane -- Membrane curvature dictates SNARE size -- Disassembly of membrane-associated SNARE complex -- CD spectroscopy confirm membrane requirement for t-/v-SNARE assembly -- SNAREs br ing opposing bilayers closer for calcium bridging -- Membrane lipids influence SNARE complex assembly-disassembly -- Vesicle swelling and content expulsion during cell secretion -- Secretory vesicle swelling is required for intravesicular content expulsion -- Molecular mechanism of secretory vesicle swelling -- Presence of beta receptors at the secretory vesicle membrane -- Conclusion and future studies. | |
| 520 | |a Understanding live cells at the single molecule level is the most important and single major challenge facing biology and medicine today. Over the past 15 years, there has been a renewed understanding of living cells at the molecular level. Atomic Force Microscopy, Laser Force Microscopy, single secretory vesicle patch clamp studies, highresolution electron microscopy, and x-ray diffraction, are some of the tools now being used to unravel the intricacies of a living cell at the molecular level. Opening with an explanation of Materials and Methods, NanoCellBiology then moves through discussions of porosome discovery, calcium and SNARE-induced fusion, and vesicle swelling before winding up in a final chapter of conclusions and future studies. Succinctly packaged as SpringerBrief, this book is a must for those studying or conducting research in cell biology, biochemistry or nanobiology/nanotechnology. This book will be invaluable to faculty & graduate students involved in Nano Courses; Cell Biology Courses; Biophysics Courses; and Biochemistry Courses as well as practicing Cell Biologists, Biochemists and BioPhysicists. | ||
| 650 | 0 | |a Biophysics. | |
| 650 | 0 | |a Nanoscience. | |
| 650 | 0 | |a Cytology. | |
| 650 | 1 | 4 | |a Bioanalysis and Bioimaging. |
| 650 | 2 | 4 | |a Nanophysics. |
| 650 | 2 | 4 | |a Cell Biology. |
| 710 | 2 | |a SpringerLink (Online service) | |
| 773 | 0 | |t Springer Nature eBook | |
| 776 | 0 | 8 | |i Printed edition: |z 9781461424390 |
| 776 | 0 | 8 | |i Printed edition: |z 9781461424376 |
| 830 | 0 | |a SpringerBriefs in Biological Imaging, |x 2193-3367 | |
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| 950 | |a Biomedical and Life Sciences (SpringerNature-11642) | ||
| 950 | |a Biomedical and Life Sciences (R0) (SpringerNature-43708) | ||