RAMPs

 Among the many GPCRs discovered, the calcitonin family of receptors comprise of members that regulate a number of physiological processes and are involved in many pathological conditions. Therefore, understanding how these receptors function is a critical question in the field. When Foord and his c...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Spielman, William S. (Editor ), Parameswaran, Narayanan (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2012.
Edición:1st ed. 2012.
Colección:Advances in Experimental Medicine and Biology, 744
Temas:
Medicine-Research.
Biology-Research.
Cytology.
Biomedical Research.
Cell Biology.
Acceso en línea:Texto Completo

MARC

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250 |a 1st ed. 2012. 
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300 |a XVIII, 116 p. 14 illus.  |b online resource. 
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490 1 |a Advances in Experimental Medicine and Biology,  |x 2214-8019 ;  |v 744 
505 0 |a Introduction to RAMPs -- RAMPs and CGRP Receptors -- Regulation of GPCR Trafficking by RAMPs -- Regulation of Calcium Sensing Receptor Trafficking by RAMPs -- Understanding RAMPs through Genetically Engineered Mouse Models -- RAMPs as Drug Targets -- Ramp Like Proteins: RTP and REEP Family of Proteins -- Regulation of RAMP Expression in Diseases -- Perspectives on some Recent Studies on RAMPs. 
520 |a  Among the many GPCRs discovered, the calcitonin family of receptors comprise of members that regulate a number of physiological processes and are involved in many pathological conditions. Therefore, understanding how these receptors function is a critical question in the field. When Foord and his colleagues discovered that a single transmembrane protein called Receptor Activity Modifying Proteins (RAMPs) could modulate the surface expression of GPCRs of the calcitonin family, it widely opened the field of receptor life cycle. Hundreds of studies have confirmed the importance of RAMPs in the life cycle of this receptor family. Receptor biology is a rapidly expanding field and with the advances in cell and molecular biology and in vivo techniques, it is very likely that the field of RAMPs will explode further and many unanswered questions will be answered with in the next few years. 
650 0 |a Medicine-Research. 
650 0 |a Biology-Research. 
650 0 |a Cytology. 
650 1 4 |a Biomedical Research. 
650 2 4 |a Cell Biology. 
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700 1 |a Parameswaran, Narayanan.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
710 2 |a SpringerLink (Online service) 
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950 |a Biomedical and Life Sciences (R0) (SpringerNature-43708) 

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