Formulating Poorly Water Soluble Drugs

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A pharmaceutical scientist's approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound's physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, ad...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Williams III, Robert O. (Editor ), Watts, Alan B. (Editor ), Miller, Dave A. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2012.
Edición:1st ed. 2012.
Colección:AAPS Advances in the Pharmaceutical Sciences Series, 3
Temas:
Pharmaceutical chemistry.
Pharmaceutics.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Route-Specific Challenges in Delivery of Poorly Water Soluble Drugs
  • Optimizing the Formulation of Poorly Water Soluble Drugs
  • Solid-State Techniques for Improving Solubility
  • Mechanical Particle Size Reduction Techniques
  • Solubilized Formulations
  • Injectable Formulations of Poorly Water Soluble Drugs
  • Design and Development of Self-Emulsifying Lipid Formulations for Improving Oral Bioavailability of Poorly Water-Soluble and Lipophilic Drugs
  • Structured Development Approach for Amorphous Systems
  • Melt Extrusion
  • Spray Drying Technology
  • Pharmaceutical Cryogenic Technologies
  • Precipitation Technologies for Nanoparticle Production
  • Emerging Technologies to Increase the Bioavailability of Poorly Water Soluble Drugs
  • Regulatory Considerations for Development and Commercialization of Poorly Water Soluble Drugs.

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