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Endocrine FGFs and Klothos

Fibroblast growth factors (FGFs) have been recognized primarily as autocrine/paracrine factors that regulate embryonic development and organogenesis. However, recent studies have revealed that some FGFs function as endocrine factors and regulate various metabolic processes in adulthood. Such FGFs, c...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Kuro-o, Makoto (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2012.
Edición:1st ed. 2012.
Colección:Advances in Experimental Medicine and Biology, 728
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • The Structural Biology of the FGF19 Subfamily
  • Klotho and bKlotho
  • FGF23 and Syndromes of Abnormal Renal Phosphate Handling
  • Evidence For FGF23 Involvement in a Bone‑Kidney Axis Regulating Bone Mineralization and Systemic Phosphate and Vitamin D Homeostasis
  • FGF23, Klotho and Vitamin D Interactions: What Have We Learned from In Vivo Mouse Genetics Studies?
  • FGF23 and the Parathyroid
  • Regulation of Ion Channels by Secreted Klotho
  • FGF23 in Chronic Kidney Disease
  • Secreted Klotho and Chronic Kidney Disease
  • FGF23 as a Novel Therapeutic Target
  • Physiology of FGF15/19
  • FGF19 and Cancer
  • Understanding the Structure‑Function Relationship Between FGF19 and its Mitogenic and Metabolic Activities
  • FGF21 as a Therapeutic Reagent.