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Natural Killer T cells Balancing the Regulation of Tumor Immunity /
Natural killer T (NKT) cells are CD1d-restricted T cells that respond to lipid, not protein, antigens presented by CD1d, which is a non-classical MHC class I-like molecule. This relatively small but pivotal T cell population bridges the gap between innate and adaptive immunity by rapidly produce la...
| Clasificación: | Libro Electrónico |
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| Autor Corporativo: | |
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York, NY :
Springer New York : Imprint: Humana,
2012.
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| Edición: | 1st ed. 2012. |
| Colección: | Cancer Drug Discovery and Development,
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| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- Preface.- Introduction: Mechanisms of NKT cell-mediated adjuvant activity and function of iPS-derived NKT cells
- Structure and Recognition of Antigens for Invariant NKT Cells
- Invariant NKT cell-based vaccine strategies
- Immune regulation of tumor immunity by NKT cells
- The Regulation of CD1d+ and CD1d- tumors by NKT Cells
- DC-based immunotherapy targeting NKT cells
- Therapeutic Approaches Utilising NKT Cells
- NKT Cells of Cancer Patients & How Models can Inform Therapeutic Plans
- Understanding the role of Natural Killer T (NKT) cells in hematologic malignancies: progress and challenges
- Clinical trials with α-galactosylceramide (KRN7000) in advanced cancer
- Clinical trials of invariant Natural Killer T cell-based immunotherapy for cancer
- Index. .