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Insulin-like Growth Factors and Cancer From Basic Biology to Therapeutics /

The insulin-like growth factor system has been shown to play a critical role in cancer development and progression. Insulin-like Growth Factors and Cancer: From Basic Biology to Therapeutics, specifically brings these aspects to the reader. The volume covers the epidemiological aspects of the relati...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: LeRoith, Derek (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer US : Imprint: Humana, 2012.
Edición:1st ed. 2012.
Colección:Cancer Drug Discovery and Development,
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Preface
  • Epidemiology of IGF-1 and Cancer
  • Aging and Cancer: The IGF-I Connection
  • Obesity, Type 2 Diabetes and Cancer
  • IGF System and Breast Cancer
  • The Role of Insulin-Like Growth Factor Signaling in Prostate Cancer Development and Progression
  • Mouse Models of IGF-1 Deficiency
  • Insulin-like Growth Factor Signaling in Pediatric Sarcomas
  • Cancer Genes, Tumor Suppressors, and Regulation of IGF-1R Expression in Cancer
  • Mouse Models of IGF-1R and Cancer
  • Targeting the Insulin-Like Growth Factor-I Receptor in Cancer Therapy
  • Targeting Insulin-like Growth Factor (IGF-1R) and Insulin Receptor Signaling by Tyrosine Kinase Inhibitors in Cancer
  • Calories and Cancer:  The Role of Insulin-like Growth Factor
  • Cancer Cell Metabolism
  • Overlaps between the Insulin and IGF-1R and Cancer
  • Index.