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Designs for Clinical Trials Perspectives on Current Issues /
Statistical methods for clinical trials have been an area of active research in Biostatistics since the first modern clinical trials were mounted in 1946 by the British Medical Research Council in whooping cough and tuberculosis. Often, the participants in clinical trials suffer from potentially fa...
| Clasificación: | Libro Electrónico |
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| Autor Corporativo: | |
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York, NY :
Springer New York : Imprint: Springer,
2012.
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| Edición: | 1st ed. 2012. |
| Colección: | Applied Bioinformatics and Biostatistics in Cancer Research,
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| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- New designs for phase I dose finding studies
- Phase II/III designs for trials
- Design issues for clinical studies with genomic measurements
- Designing studies with longitudinal measurements subject to dropout
- Issues in sample size re-estimation
- Adaptive designs
- The design of non-inferiority trials
- Issues in the design of HIV prevention trials
- Randomization algorithms
- Sequential designs for phase III studies
- Case studies of difficult designs
- Ethical issues in the design of trials
- Index.