Translational Research Methods for Diabetes, Obesity and Cardiometabolic Drug Development A Focus on Early Phase Clinical Studies /

This book aims to aid the selection of the most appropriate techniques for use in early phase (1 and 2) clinical studies of new drugs for diabetes, obesity, and related cardiometabolic disease. Clinical research methods for assessing the pharmacokinetics and pharmacodynamics of new diabetes drugs, e...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Krentz, Andrew J. (Editor ), Heinemann, Lutz (Editor ), Hompesch, Marcus (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Springer London : Imprint: Springer, 2015.
Edición:1st ed. 2015.
Temas:
Medical sciences.
Internal medicine.
Diseases.
Pharmacology.
Pharmaceutical chemistry.
Health Sciences.
Internal Medicine.
Pharmaceutics.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • 1. Review of physiology/pathophysiology
  • 2. Methods for assessing insulin action in humans
  • 3. Assessment of insulin secretion
  • 4. Measurement of ectopic fat in liver and muscle using magnetic resonance spectroscopy
  • 5. Isotopic tracers for the measurement of metabolic flux
  • 6. Measuring food intake in clinical drug development
  • 7. Measurement of energy expenditure
  • 8. Assessment of body composition
  • 9.  Assessment of cardiovascular safety of new diabetes drugs.

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