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Drug Product Development for the Back of the Eye

This comprehensive volume discusses approaches for a systematic selection of delivery systems for various classes of therapeutic agents including small molecule, protein, and nucleic acid drugs. Specific topics covered in this book include: Solution, suspension, gel, nanoparticle, microparticle, and...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Kompella, Uday B. (Editor ), Edelhauser, Henry F. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer US : Imprint: Springer, 2011.
Edición:1st ed. 2011.
Colección:AAPS Advances in the Pharmaceutical Sciences Series, 2
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Selection of Drug Delivery Approaches for the Back of the Eye: Opportunities and Unmet Needs
  • Microdialysis for Vitreal Pharmacokinetics
  • Fluorophotometry for Pharmacokinetic Assessment
  • Systemic Route for Retinal Drug Delivery: Role of the Blood-Retinal Barrier
  • Topical Drug Delivery to the Back of the Eye
  • Principles of Retinal Drug Delivery from Within the Vitreous
  • Transscleral Drug Delivery
  • Suprachoroidal and Intrascleral Drug Delivery
  • Advances in Biodegradable Ocular Drug Delivery Systems
  • Microparticles as Drug Delivery Systems for the Back of the Eye
  • Nanotechnology and Nanoparticles
  • Hydrogels for Ocular Posterior Segment Drug Delivery
  • Refillable Devices for Therapy of Ophthalmic Diseases
  • Targeted Drug Delivery to the Eye Enabled by Microneedles
  • Ocular Iontophoresis
  • Drug and Gene Therapy Mediated by Physical Methods
  • Protein Drug Delivery and Formulation Development
  • Drug Suspension Development for the Back of the Eye
  • Regulatory Considerations in Product Development for Back of the Eye
  • Clinical Endpoints for Back of the Eye Diseases
  • Druggable Targets and Therapeutic Agents for Disorders of the Back of the Eye
  • Development of Bile Acids as Anti-Apoptotic and Neuroprotective Agents in Treatment of Ocular Disease.