Cargando…
Drug Product Development for the Back of the Eye
This comprehensive volume discusses approaches for a systematic selection of delivery systems for various classes of therapeutic agents including small molecule, protein, and nucleic acid drugs. Specific topics covered in this book include: Solution, suspension, gel, nanoparticle, microparticle, and...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor Corporativo: | |
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York, NY :
Springer US : Imprint: Springer,
2011.
|
| Edición: | 1st ed. 2011. |
| Colección: | AAPS Advances in the Pharmaceutical Sciences Series,
2 |
| Temas: | |
| Acceso en línea: | Texto Completo |
MARC
| LEADER | 00000nam a22000005i 4500 | ||
|---|---|---|---|
| 001 | 978-1-4419-9920-7 | ||
| 003 | DE-He213 | ||
| 005 | 20220112183552.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 110725s2011 xxu| s |||| 0|eng d | ||
| 020 | |a 9781441999207 |9 978-1-4419-9920-7 | ||
| 024 | 7 | |a 10.1007/978-1-4419-9920-7 |2 doi | |
| 050 | 4 | |a RM300-666 | |
| 072 | 7 | |a MMG |2 bicssc | |
| 072 | 7 | |a MED071000 |2 bisacsh | |
| 072 | 7 | |a MKG |2 thema | |
| 082 | 0 | 4 | |a 615 |2 23 |
| 245 | 1 | 0 | |a Drug Product Development for the Back of the Eye |h [electronic resource] / |c edited by Uday B. Kompella, Henry F. Edelhauser. |
| 250 | |a 1st ed. 2011. | ||
| 264 | 1 | |a New York, NY : |b Springer US : |b Imprint: Springer, |c 2011. | |
| 300 | |a XII, 592 p. |b online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file |b PDF |2 rda | ||
| 490 | 1 | |a AAPS Advances in the Pharmaceutical Sciences Series, |x 2210-738X ; |v 2 | |
| 505 | 0 | |a Selection of Drug Delivery Approaches for the Back of the Eye: Opportunities and Unmet Needs -- Microdialysis for Vitreal Pharmacokinetics -- Fluorophotometry for Pharmacokinetic Assessment -- Systemic Route for Retinal Drug Delivery: Role of the Blood-Retinal Barrier -- Topical Drug Delivery to the Back of the Eye -- Principles of Retinal Drug Delivery from Within the Vitreous -- Transscleral Drug Delivery -- Suprachoroidal and Intrascleral Drug Delivery -- Advances in Biodegradable Ocular Drug Delivery Systems -- Microparticles as Drug Delivery Systems for the Back of the Eye -- Nanotechnology and Nanoparticles -- Hydrogels for Ocular Posterior Segment Drug Delivery -- Refillable Devices for Therapy of Ophthalmic Diseases -- Targeted Drug Delivery to the Eye Enabled by Microneedles -- Ocular Iontophoresis -- Drug and Gene Therapy Mediated by Physical Methods -- Protein Drug Delivery and Formulation Development -- Drug Suspension Development for the Back of the Eye -- Regulatory Considerations in Product Development for Back of the Eye -- Clinical Endpoints for Back of the Eye Diseases -- Druggable Targets and Therapeutic Agents for Disorders of the Back of the Eye -- Development of Bile Acids as Anti-Apoptotic and Neuroprotective Agents in Treatment of Ocular Disease. | |
| 520 | |a This comprehensive volume discusses approaches for a systematic selection of delivery systems for various classes of therapeutic agents including small molecule, protein, and nucleic acid drugs. Specific topics covered in this book include: Solution, suspension, gel, nanoparticle, microparticle, and implant dosage forms Refillable and microneedle devices Intravitreal, suprachoroidal, intrascleral, transscleral, systemic, and topical routes of delivery Physical methods including iontophoresis for drug delivery Rational selection of routes of administration and delivery systems Noninvasive and continuous drug monitoring Clinical endpoints and regulatory path to drug product development Emerging and existing drugs and drug targets Drug Product Development for the Back of the Eye is authored by renowned ocular drug delivery experts, representing academic, clinical, and industrial organizations and serves as indispensable resource for ophthalmic researchers, drug formulation scientists, drug delivery and drug disposition scientists, as well as clinicians involved in designing and developing novel therapeutics for the back of the eye diseases. This book is also relevant for students in various disciplines including ophthalmology, pharmaceutical sciences, drug delivery, and biomedical engineering. Uday B. Kompella, Ph.D., Professor of Pharmaceutical Sciences & Ophthalmology, University of Colorado, developed functionalized nanoparticles, nanoporous microparticles, microparticles, injectable implants, dendrimers, liposomes, and in situ forming gels for the eye. He is a Fellow of the American Association of Pharmaceutical Scientists (2005) and the Association for Research in Vision and Ophthalmology (2010). He received Distinguished Scientist (2006) Award from the University of Nebraska. Henry F. Edelhauser, Ph.D., Professor of Ophthalmology, Emory University, made pioneering contributions towards transcorneal, transscleral, and suprachoroidal drug delivery to the eye. He is a recipient of the Castroviejo Medal and the Alcon Research Award (1999), American Academy of Ophthalmology Senior Achievement Award (2000), and the Procter Medal (2005) for his outstanding ophthalmic translational research. He served as the president of the Association for Research in Vision and Ophthalmology (1990-91). | ||
| 650 | 0 | |a Pharmacology. | |
| 650 | 0 | |a Ophthalmology. | |
| 650 | 0 | |a Pharmaceutical chemistry. | |
| 650 | 1 | 4 | |a Pharmacology. |
| 650 | 2 | 4 | |a Ophthalmology. |
| 650 | 2 | 4 | |a Pharmaceutics. |
| 700 | 1 | |a Kompella, Uday B. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 700 | 1 | |a Edelhauser, Henry F. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 710 | 2 | |a SpringerLink (Online service) | |
| 773 | 0 | |t Springer Nature eBook | |
| 776 | 0 | 8 | |i Printed edition: |z 9781441999191 |
| 776 | 0 | 8 | |i Printed edition: |z 9781461428190 |
| 776 | 0 | 8 | |i Printed edition: |z 9781441999214 |
| 830 | 0 | |a AAPS Advances in the Pharmaceutical Sciences Series, |x 2210-738X ; |v 2 | |
| 856 | 4 | 0 | |u https://doi.uam.elogim.com/10.1007/978-1-4419-9920-7 |z Texto Completo |
| 912 | |a ZDB-2-SBL | ||
| 912 | |a ZDB-2-SXB | ||
| 950 | |a Biomedical and Life Sciences (SpringerNature-11642) | ||
| 950 | |a Biomedical and Life Sciences (R0) (SpringerNature-43708) | ||