Characterization of Protein Therapeutics using Mass Spectrometry

Protein therapeutics' high efficacy, safety, and ability to treat life-threatening diseases such as cancer, inflammation and genetic disorders have revolutionized modern medicine. In 2012, 200 companies competed in this $90 billion year industry.   In Characterization of Protein Therapeutics us...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Chen, Guodong (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer US : Imprint: Springer, 2013.
Edición:1st ed. 2013.
Temas:
Mass spectroscopy.
Proteins .
Pharmaceutical chemistry.
Biotechnology.
Medical genetics.
Materials-Analysis.
Mass Spectrometry.
Protein Biochemistry.
Pharmaceutics.
Medical Genetics.
Characterization and Analytical Technique.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Characterization of Protein Therapeutics by Mass Spectrometry: Recent Developments and Future Directions
  • The Use of Mass Spectrometry to Characterize the Metabolism of Peptide Therapeutics
  • Quantitative Analysis of Biologics Using Mass Spectrometry
  • Maximizing Structural Information from Whole Protein Tandem Mass Spectrometry
  • Disulfide Linkages of an Albumin Fusion Protein
  • Detailed Structural Characterization of Monoclonal Antibodies
  • Application of Protein Mass Spectrometry in Impurity and Degradant Characterization
  • Mass Spectrometry Methods to Analyze Higher Order Structure of Protein Therapeutics by Chemical Footprinting
  • Aglycosylations Alters Protein Conformation in Antibodies Engineered with Specific Effector Functions Using HDX-MS
  • Characterizing Biotherapeutic Protein 3D Structures by Electrospray Ion-Mobility Mass Spectrometry
  • Oxford University, Characterization of Assemblies of Proteins by Mass Spectrometry.  .

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