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|a 9781441977250
|9 978-1-4419-7725-0
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|a 10.1007/978-1-4419-7725-0
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|a Mathematical Models and Immune Cell Biology
|h [electronic resource] /
|c edited by Carmen Molina-París, Grant Lythe.
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|a 1st ed. 2011.
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|a New York, NY :
|b Springer New York :
|b Imprint: Springer,
|c 2011.
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|a XVI, 407 p.
|b online resource.
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|a text
|b txt
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|a computer
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|a Preface -- Thymocyte development -- A review of mathematical models for T cell receptor triggering and antigen discrimination -- Dynamic tuning of T cell receptor specificity by co-receptors and costimulation -- T cell activation and function: role of signal strength -- The cyton model for lymphocyte proliferation and differentiation -- Modeling itravital two-photon data of lymphocyte migration and interaction -- Modeling lymphocyte dynamics in vivo -- Continuous-time birth and death processes: diversity maintenance of naïve T cells in the periphery -- Multivariate competition processes: a model for two competing T cell clonotypes -- Stochastic modeling of T Cell homeostasis for two competing clonotypes via the master equation -- Dendritic cell migration in the intestinal tract -- Reassessing germinal center reaction concepts -- B cell strategies of Ag recognition in a stratified immune system -- Dynamics of Peripheral regulatory and effector T cells competing for antigen presenting cells -- Mathematical models of the role of IL-2 in the interactions between helper and regulstory CD4+ T cells -- A Physicist's approach to immunology -- Timescales of the adaptive immune response -- Using mathematical models to explore the role of cytoxic T lymphocytes in HIV infection -- Viral immunity and persistence -- Index.
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|a Mathematical immunology is in a period of rapid expansion and excitement. At recent meetings, a common language and research direction has emerged amongst a world-class group of scientists and mathematicians. Mathematical Models and Immune Cell Biology aims to communicate these new ideas to a wider audience. The reader will be exposed to a variety of tools and methods that go hand-in-hand with the immunological processes being modeled. This volume contains chapters, written by immunologists and mathematicians, on thymocytes, on T cell interactions, activation, proliferation and homeostasis, as well as on dendritic cells, B cells and germinal centers. Chapters are devoted to measurement and imaging methods and to HIV and viral infections.
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|a Immunology.
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|a Bioinformatics.
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|a Proteins.
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|a Immunology.
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|a Computational and Systems Biology.
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|a Proteins.
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|a Molina-París, Carmen.
|e editor.
|4 edt
|4 http://id.loc.gov/vocabulary/relators/edt
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|a Lythe, Grant.
|e editor.
|4 edt
|4 http://id.loc.gov/vocabulary/relators/edt
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|a SpringerLink (Online service)
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|t Springer Nature eBook
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|i Printed edition:
|z 9781441977243
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|i Printed edition:
|z 9781493901234
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|i Printed edition:
|z 9781441977267
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|u https://doi.uam.elogim.com/10.1007/978-1-4419-7725-0
|z Texto Completo
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|a Biomedical and Life Sciences (SpringerNature-11642)
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|a Biomedical and Life Sciences (R0) (SpringerNature-43708)
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