Insertional Mutagenesis Strategies in Cancer Genetics

Over the past decades, insertional mutagenesis has played an important contribution to our understanding of cancer. Initially, the action of slow transforming retroviruses was used to identify endogenous cellular oncogenes (e.g. Myc, Myb). These observations sparked a series of experiments that even...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Dupuy, Adam J. (Editor ), Largaespada, David A. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2011.
Edición:1st ed. 2011.
Temas:
Cancer.
Medical genetics.
Pharmacology.
Cancer Biology.
Medical Genetics.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Chapter 1: Introduction: Author: Anton Berns (Netherlands Cancer Institute)
  • Chapter 2: Retroviral mutagenesis in mouse leukemia/lymphoma: Author: David Largaespada, Ph.D. (University of Minnesota)
  • Chapter 3: MMTV models of breast cancer: Author: John Hilkens (NKI)
  • Chapter 4: Retroviral mutagenesis in other organisms: Author: Michael Dvorak (Inst. Of Molecular Genetics, Prague, Czech Rep.)
  • Chapter 5: Sleeping Beauty models of cancer: Author: Adam J. Dupuy, Ph.D. (University of Iowa)
  • Chapter 6: Insertional mutagenesis in gene therapy patients: Author: David Williams, M.D. (Cincinnati Children's Hospital)
  • Chapter 7: Bioinformatics of high throughput insertional mutagenesis: Author: Keiko Akagi (NCI-Frederick).

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