Cargando…

Obesity Before Birth Maternal and prenatal influences on the offspring /

Obesity obeys the First Law of Thermodynamics. The routine assumption is that obesity is the result of a mismatch between calories in and calories out; in other words, the result of two divergent behaviors. However, there is mounting evidence that biochemical forces can drive obligate weight gain, a...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Lustig, Robert H. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer US : Imprint: Springer, 2011.
Edición:1st ed. 2011.
Colección:Endocrine Updates ; 30
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Preface
  • Obesity: nature or nurture?
  • The contribution of heredity to clinical obesity
  • Monogenetic disorders within the energy balance pathway
  • Ciliary syndromes and obesity
  • Genome-wide association studies and human population obesity
  • Known clinical epigenetic disorders with an obesity phenotype: Prader-Willi Syndrome and the GNAS locus
  • Evidence for epigenetic changes as a cause of clinical obesity
  • Epigenetic changes associated with intrauterine growth retardation and adipogenesis
  • Exposure to diabetes in utero, offspring growth, and risk for obesity
  • Maternal weight gain during pregnancy and obesity in the offspring
  • Intrauterine growth restriction, small for gestational age, and experimental obesity
  • Experimental models of maternal obesity and high-fat diet during pregnancy and programmed obesity in the offspring
  • High carbohydrate intake only during the suckling period results in adult-onset obesity in mother as well as offspring
  • Prenatal stress, glucocorticoids, and the metabolic syndrome
  • Hypothalamic maldevelopment and developmental programming
  • Adipocyte development and experimental obesity
  • The obesogen hypothesis of obesity: overview and human evidence
  • Perinatal exposure to endocrine disrupting chemicals with estrogenic activity and the development of obesity
  • The role of environmental obesogens in the obesity epidemic.