Cargando…

Neurochemical Aspects of Neurotraumatic and Neurodegenerative Diseases

Neurotraumatic (stroke, spinal cord trauma, and traumatic head injury) and neurodegenerative diseases (Alzheimer disease, Parkinson disease, Amyotrophic Lateral Sclerosis, Huntington disease, and prion disease) are afflicting aging Americans with increasing frequency. These diseases result in acute,...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Farooqui, Akhlaq A. (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2010.
Edición:1st ed. 2010.
Temas:
Acceso en línea:Texto Completo

MARC

LEADER 00000nam a22000005i 4500
001 978-1-4419-6652-0
003 DE-He213
005 20220113040048.0
007 cr nn 008mamaa
008 100907s2010 xxu| s |||| 0|eng d
020 |a 9781441966520  |9 978-1-4419-6652-0 
024 7 |a 10.1007/978-1-4419-6652-0  |2 doi 
050 4 |a RC321-580 
072 7 |a PSAN  |2 bicssc 
072 7 |a MED057000  |2 bisacsh 
072 7 |a PSAN  |2 thema 
082 0 4 |a 612.8  |2 23 
100 1 |a Farooqui, Akhlaq A.  |e author.  |4 aut  |4 http://id.loc.gov/vocabulary/relators/aut 
245 1 0 |a Neurochemical Aspects of Neurotraumatic and Neurodegenerative Diseases  |h [electronic resource] /  |c by Akhlaq A. Farooqui. 
250 |a 1st ed. 2010. 
264 1 |a New York, NY :  |b Springer New York :  |b Imprint: Springer,  |c 2010. 
300 |a XXIII, 401 p.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
505 0 |a Neurodegeneration in Neural Trauma, Neurodegenerative Diseases, and Neuropsychiatric Disorders -- Neurochemical Aspects of Ischemic Injury -- Potential Neuroprotective Strategies for Ischemic Injury -- Neurochemical Aspects of Spinal Cord Injury -- Potential Neuroprotective Strategies for Experimental Spinal Cord Injury -- Neurochemical Aspects of Traumatic Brain Injury -- Potential Neuroprotective Strategies for Traumatic Brain Injury -- Neurochemical Aspects of Neurodegenerative Diseases -- Potential Therapeutic Strategies for Neurodegenerative Diseases -- Perspective and Direction for Future Developments on Neurotraumatic and Neurodegenerative Diseases. 
520 |a Neurotraumatic (stroke, spinal cord trauma, and traumatic head injury) and neurodegenerative diseases (Alzheimer disease, Parkinson disease, Amyotrophic Lateral Sclerosis, Huntington disease, and prion disease) are afflicting aging Americans with increasing frequency. These diseases result in acute, as well as gradual and progressive neurodegeneration, leading to brain dysfunction. Known risk factors for stroke and neurodegenerative diseases include increasing age, genetic polymorphisms, endocrine dysfunction, oxidative stress, neuroinflammation, excitotoxicity, infection, and exposure to neurotoxins. In contrast, spinal cord trauma and traumatic brain injury due to motorcycle and car accidents are major causes of death and disability among young people below the mid-thirties. Although molecular mechanisms involved in the pathogenesis of neurotraumatic and neurodegenerative diseases remain elusive, oxidative stress, excitotoxicity, inflammation, misfolding, aggregation, and accumulation of proteins, perturbed Ca2+ homeostasis, and apoptosis have been implicated as possible causes of neurodegeneration in the above neurological disorders. In 2005, the global prevalence of neurotraumatic and neurodegenerative diseases was estimated at 35 million, with more than seven million new cases occurring each year. It is calculated that the number of people affected with neurotraumatic and neurodegenerative diseases will double every 20 years, to 100 million by 2040, if a cure is not discovered. More than 60% of dementia cases are due to Alzheimer disease. Today, approximately six million individuals in the US suffer from Alzheimer disease alone, representing one in eight individuals over the age of 65-70. Neurochemical Aspects of Neurotraumatic and Neurodegenerative Diseases presents readers with a cutting edge and comprehensive overview of neurochemical aspects of neurotraumatic and neurodegenerative diseases and their potential therapeutic strategies in a manner that is useful not only to graduate students and teachers, but also to research scientists and clinicians. About the Author: Dr. Akhlaq A. Farooqui is a leader in the field of brain phospholipases, lipid mediators, glutamate neurotoxicity and neurological disorders. Dr. Farooqui has authored five monographs: Glycerophospholipids in Brain: Phospholipase A2 in Neurological Disorders (2007); Neurochemical Aspects of Excitotoxicity (2008); Metabolism and Functions of Bioactive Ether Lipids in Brain (2008); Hot Topics in Neural Membrane Lipidology (2009), and Beneficial Effects of Fish Oil on Human Brain (2009). All monographs are published by Springer. Dr. Farooqui has also edited two books: Biogenic Amines: Pharmacological, Neurochemical and Molecular Aspects in the CNS Nova Science Publishers, Hauppauge, N.Y (2010) and Molecular Aspects of Neurodegeneration and Neuroprotection, Bentham Science Publishers Ltd (2010). 
650 0 |a Neurosciences. 
650 0 |a Neurology . 
650 0 |a Neurochemistry. 
650 1 4 |a Neuroscience. 
650 2 4 |a Neurology. 
650 2 4 |a Neurochemistry. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer Nature eBook 
776 0 8 |i Printed edition:  |z 9781441966513 
776 0 8 |i Printed edition:  |z 9781489982568 
776 0 8 |i Printed edition:  |z 9781441966537 
856 4 0 |u https://doi.uam.elogim.com/10.1007/978-1-4419-6652-0  |z Texto Completo 
912 |a ZDB-2-SBL 
912 |a ZDB-2-SXB 
950 |a Biomedical and Life Sciences (SpringerNature-11642) 
950 |a Biomedical and Life Sciences (R0) (SpringerNature-43708)