Scleroderma From Pathogenesis to Comprehensive Management /

This essential resource presents the most up-to-date information on scleroderma. A clear and concise synthesis of current concepts in pathogenesis and modern approaches to management, this book is comprised of the authoritative work of international experts. With an integrated multidisciplinary appr...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Varga, John (Editor ), Denton, Christopher P. (Editor ), Wigley, Fredrick M. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2012.
Edición:1st ed. 2012.
Temas:
Rheumatology.
Internal medicine.
Respiratory organs-Diseases.
Internal Medicine.
Pneumology.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Foreword
  • Preface
  • Historical Perspective.-Therapeutic evolution: a professor's view
  • Overview: Epidemiology, Genetics and Classification.-Epidemiology and Environmental Risk Factors.- Genetic Factors
  • Disease Subsets in Clinical Practice.-Evolving Concepts of Diagnosis and Classification
  • Disease Classification using Molecular Signatures.-Localized Scleroderma
  • Juvenile Systemic Scleroderma.-Scleroderma Mimics
  • Localized Forms of Scleroderma in Adults.-Overview: Integrated Pathogenesis
  • Immunological Mechanisms.-Innate Immunity
  • Autoantibodies in Pathogenesis
  • The Clinical Aspects of Autoantibodies
  • Mechanisms of Vascular Disease.-Vascular Biomarkers
  • Mechanisms of Fibrosis
  • Fibrosis: Insights from the stiff skin syndrome
  • Biomarkers of Fibrosis
  • Overview of Animal Models.-Overview: Cardiovascular Manifestations and Management.-Raynaud Phenomenon.-Nailfold Capillaroscopy
  • Systemic Vascular Disease
  • Scleroderma Renal Crisis
  • Cardiac Involvement.-Erectile Dysfunction.-Overview: Pulmonary manifestations and management.-Clinical Assessment of Lung Disease
  • Computerized Tomography of Interstitial Lung Disease.-Treatment of interstitial lung disease.-Clinical Assessment of Pulmonary Hypertension.-Treatment of Pulmonary Hypertension
  • Complex Challenges of Pulmonary Hypertension
  • Overview: Gastrointestinal Manifestations and Management
  • Upper Gastrointestinal Tract.-Small and Large Intestinal Involvement.-Evaluation and Management of Skin Disease.-Skeletal Muscle Involvement.-  Tendons, Joints and Bone
  • Pregnancy.-Overlooked Manifestations
  • Principles of Management.-Immunomodulatory Therapies.-Cell-Based Therapies
  • Investigative Approaches to Drug Therapy.-Complementary and alternate medicine approaches.-Physical and occupational therapy
  • Evaluation and Management of Psychosocial Issues.-Issues in Clinical Trial Design
  • Measuring Disease Activity
  • Patient Reported Outcomes. .

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