Cargando…
Inflammation and Retinal Disease: Complement Biology and Pathology
Numerous studies have pointed to the key role of complement in the pathogenesis of retinal disease, particularly age-related macular degeneration (AMD). Reports about new gene associations and links to other physiological pathways are emerging almost on a weekly base. Several promising clinical cand...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor Corporativo: | |
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York, NY :
Springer New York : Imprint: Springer,
2010.
|
| Edición: | 1st ed. 2010. |
| Colección: | Advances in Experimental Medicine and Biology,
703 |
| Temas: | |
| Acceso en línea: | Texto Completo |
MARC
| LEADER | 00000nam a22000005i 4500 | ||
|---|---|---|---|
| 001 | 978-1-4419-5635-4 | ||
| 003 | DE-He213 | ||
| 005 | 20220113090814.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 100825s2010 xxu| s |||| 0|eng d | ||
| 020 | |a 9781441956354 |9 978-1-4419-5635-4 | ||
| 024 | 7 | |a 10.1007/978-1-4419-5635-4 |2 doi | |
| 050 | 4 | |a RE1-994 | |
| 072 | 7 | |a MJQ |2 bicssc | |
| 072 | 7 | |a MED063000 |2 bisacsh | |
| 072 | 7 | |a MJQ |2 thema | |
| 082 | 0 | 4 | |a 617.7 |2 23 |
| 245 | 1 | 0 | |a Inflammation and Retinal Disease: Complement Biology and Pathology |h [electronic resource] / |c edited by John D. Lambris, Anthony P. Adamis. |
| 250 | |a 1st ed. 2010. | ||
| 264 | 1 | |a New York, NY : |b Springer New York : |b Imprint: Springer, |c 2010. | |
| 300 | |a XIV, 170 p. |b online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file |b PDF |2 rda | ||
| 490 | 1 | |a Advances in Experimental Medicine and Biology, |x 2214-8019 ; |v 703 | |
| 505 | 0 | |a The Case for Complement and Inflammation in AMD: Open Questions -- The Role of Complement in AMD -- Multiple Interactions of Complement Factor H with Its Ligands in Solution: A Progress Report -- Genetic Control of Complement Activation in Humans and Age Related Macular Degeneration -- Bisretinoids of RPE Lipofuscin: Trigger for Complement Activation in Age-Related Macular Degeneration -- The Role of the Classical Complement Cascade in Synapse Loss During Development and Glaucoma -- A Role for Complement in Glaucoma? -- The ATP-Binding Cassette Transporter ABCA4: Structural and Functional Properties and Role in Retinal Disease -- Suppression of Drusen Formation by Compstatin, a Peptide Inhibitor of Complement C3 activation, on Cynomolgus Monkey with Early-Onset Macular Degeneration -- A Targeted Inhibitor of the Complement Alternative Pathway Reduces RPE Injury and Angiogenesis in Models of Age-Related Macular Degeneration -- Complement Depletion with Humanized Cobra Venom Factor in a Mouse Model of Age-Related Macular Degeneration. | |
| 520 | |a Numerous studies have pointed to the key role of complement in the pathogenesis of retinal disease, particularly age-related macular degeneration (AMD). Reports about new gene associations and links to other physiological pathways are emerging almost on a weekly base. Several promising clinical candidates covering a wide area of potential treatment applications are in the pipelines of both industrial and academic groups. This indicates an increasing interest in complement as a therapeutic target. In view of these exciting discoveries, scientists from around the world convened at the 1st Aegean Conferences Conference on Inflammation and Retinal Disease: Complement Biology and Pathology (June 10-17, 2007) in Crete, Greece, to discuss recent advances in this rapidly-evolving field. This volume represents a collection of topics on the functions of complement in eye diseases, pathophysiology, protein structures, and complement therapeutics discussed during the conference. | ||
| 650 | 0 | |a Ophthalmology. | |
| 650 | 1 | 4 | |a Ophthalmology. |
| 700 | 1 | |a Lambris, John D. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 700 | 1 | |a Adamis, Anthony P. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 710 | 2 | |a SpringerLink (Online service) | |
| 773 | 0 | |t Springer Nature eBook | |
| 776 | 0 | 8 | |i Printed edition: |z 9781441956347 |
| 776 | 0 | 8 | |i Printed edition: |z 9781461426486 |
| 776 | 0 | 8 | |i Printed edition: |z 9781441956361 |
| 830 | 0 | |a Advances in Experimental Medicine and Biology, |x 2214-8019 ; |v 703 | |
| 856 | 4 | 0 | |u https://doi.uam.elogim.com/10.1007/978-1-4419-5635-4 |z Texto Completo |
| 912 | |a ZDB-2-SBL | ||
| 912 | |a ZDB-2-SXB | ||
| 950 | |a Biomedical and Life Sciences (SpringerNature-11642) | ||
| 950 | |a Biomedical and Life Sciences (R0) (SpringerNature-43708) | ||