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Cell-Extracellular Matrix Interactions in Cancer

Cells require interactions with extracellular matrix (ECM) components in order to undergo normal morphogenesis with respect to organogenesis. ECM plays a significant role in regulating numerous cellular functions, like cell shape, adhesion, migration, proliferation, polarity, differentiation and apo...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Zent, Roy (Editor ), Pozzi, Ambra (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2010.
Edición:1st ed. 2010.
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • The Extracellular Matrix: An Overview
  • Integrin Structure and Function
  • Cancer in Context: Importance of the Tumor Microenvironment
  • Basement Membrane Collagens and Cancer
  • Laminins and Cancer Progression
  • Fibronectins and Their Receptors in Cancer
  • Vitronectin-Binding Integrins in Cancer
  • The Function of SPARC in Tumor Cell Biology: SPARC as a Modulator of Cell-Extracellular Matrix Interaction
  • Proteoglycans and Cancer
  • Tetraspanins in Cancer
  • The Role of Integrin-Linked Kinase in Cancer Development and Progression
  • Focal Adhesion Kinase with the Interacting Proteins and Signaling in Cancer.