Imaging in CNS Drug Discovery and Development Implications for Disease and Therapy /

Imaging is a key area of translational research that provides a unique bridge from the laboratory to the clinic as the same techniques and technologies can applied across the various phases of drug development. Neuroimaging is now central to research and drug development in the neurosciences since i...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Borsook, David (Editor ), Beccera, Lino R. (Editor ), Bullmore, Edward (Editor ), Hargreaves, Richard J. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2009.
Edición:1st ed. 2009.
Temas:
Pharmacology.
Radiology.
Biotechnology.
Neurosciences.
Cancer.
Neuroscience.
Cancer Biology.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Background
  • The Challenges and Opportunities
  • Imaging of CNS Systems: Importance for Drug Development
  • Imaging Approaches
  • Anatomical Imaging: Volumetric Analysis
  • Diffusion Tensor Imaging and Drug Development
  • Functional Magnetic Resonance Imaging in Drug Development
  • Magnetic Resonance Imaging of Pharmacological Systems
  • Molecular Imaging: Basic Approaches
  • Chemical Imaging: Magnetic Resonance Spectroscopy: The Basics
  • Imaging CNS Drug Action
  • Animal Imaging
  • Incorporating Functional MRI into Clinical Pharmacology Trials
  • Imaging Placebo Responses in the Brain
  • Structural Imaging of Drug Actions in Neurodegenerative Diseases
  • Molecular Imaging of the CNS: Drug Actions
  • Imaging CNS Disease States
  • Translational MRI in CNS Drug Discovery
  • In Vivo Mouse Imaging and Spectroscopy in Drug Discovery
  • Neuroimaging in Understanding Chronic Pain Mechanisms and the Development of New Therapies
  • Neuroimaging Human Drug Addiction
  • Anxiety: Uncover Roles of Stress Related Genes by Imaging Genetics
  • Imaging CNS Disease States: Alzheimer's Disease
  • Brain Development and CNS Plasticity
  • Imaging in CNS Disease States: PTSD
  • Integrative Processes
  • Integrative Processes: Neuroscience Clinical Imaging Biomarkers
  • Reasons to Believe: The Potential of Imaging in CNS Drug Development.

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