Epigenomics

Epigenetic modifications act on DNA and its packaging proteins, the histones, to regulate genome function. Manifest as the heritable methylation of DNA and as post-translational histone modifications, these molecular flags influence the architecture and integrity of the chromosome, the accessibility...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Ferguson-Smith, Anne C. (Editor ), Greally, Ph.D., John M. (Editor ), Martienssen, Rob A. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Dordrecht : Springer Netherlands : Imprint: Springer, 2009.
Edición:1st ed. 2009.
Temas:
Medicine-Research.
Biology-Research.
Biomedical Research.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Epigenomic Technologies and Analytical Approaches
  • Strategies for Epigenome Analysis
  • Sequencing the Epigenome
  • Integrating Epigenomic Results
  • Visualising the Epigenome
  • Roles of DNA, RNA and Chromatin in Epigenomics
  • The Expanding View of Cytosine Methylation
  • Structural and Biochemical Advances in Mammalian DNA Methylation
  • Epigenetic Profiling of Histone Variants
  • Epigenetic Phenomena and Epigenomics in Maize
  • Epigenetic Silencing of Pericentromeric Heterochromatin by RNA Interference in Schizosaccharomyces pombe
  • Describing Epigenomic Information in Arabidopsis
  • Role of Small RNAs in Establishing Chromosomal Architecture in Drosophila
  • MacroRNAs in the Epigenetic Control of X-Chromosome Inactivation
  • Epigenetic Control of Developmental Processes
  • Polycomb Complexes and the Role of Epigenetic Memory in Development
  • Genomic Imprinting - A Model for Roles of Histone Modifications in Epigenetic Control
  • The Epigenomic Landscape of Reprogramming in Mammals
  • Epigenetic Gene Regulation-Lessons from Globin
  • Meiotic Silencing, Infertility and X Chromosome Evolution
  • The Epigenome in Health and Disease
  • Genome Defense: The Neurospora Paradigm
  • Integrating the Genome and Epigenome in Human Disease
  • A Changing Epigenome in Health and Disease
  • Cancer Epigenomics
  • Epigenetic Modulation by Environmental Factors
  • The Relevance of Epigenetics to Major Psychosis.

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