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Evolving Methods for Macromolecular Crystallography The Structural Path to the Understanding of the Mechanism of Action of CBRN Agents /

This volume comprises papers presented at the 2005 edition of the "Crystallography of Molecular Biology" courses that have been held since 1976 at the Ettore Majorana Centre for Scientific Culture in Erice, Italy. This series of courses is renowned for bringing leaders in the field of macr...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Read, Randy J. (Editor ), Sussman, Joel L. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Dordrecht : Springer Netherlands : Imprint: Springer, 2007.
Edición:1st ed. 2007.
Colección:NATO Science Series II: Mathematics, Physics and Chemistry, Mathematics, Physics and Chemistry ; 245
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Succeeding with seeding: some practical advice
  • Expression, purification, and crystallisationof membrane proteins
  • Macromolecular cryo-crystallography
  • Processing diffraction data with mosflm
  • Sad phasing: basic concepts and high-throughput
  • Likelihood-based experimental phasing in phaser
  • Stochastic molecular replacement
  • Likelihood-based molecular replacement in phaser
  • Automated structure determination with phenix
  • Density Modification In Main
  • Ab initio phasing starting from low resolution
  • Structural genomics of mycobacterium tuberculosis: a search for function and new drug targets
  • Three-dimensional domain swapping and its relevance to conformational diseases
  • Structural bioinformatics: from protein structure to function
  • Single-particle imaging.