Cargando…

Regulation of Carcinogenesis, Angiogenesis and Metastasis by the Proprotein Convertases (PC's) A New Potential Strategy in Cancer Therapy /

Convertases are widely expressed activating enzymes involved in various physiological and pathological processes. The purpose of this book is to provide detailed and updated information on the role of these molecules in cancer. This book is the first to summarize current knowledge about the importan...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Khatib, Abdel-Majid (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Dordrecht : Springer Netherlands : Imprint: Springer, 2006.
Edición:1st ed. 2006.
Temas:
Acceso en línea:Texto Completo

MARC

LEADER 00000nam a22000005i 4500
001 978-1-4020-5132-6
003 DE-He213
005 20220113045635.0
007 cr nn 008mamaa
008 100301s2006 ne | s |||| 0|eng d
020 |a 9781402051326  |9 978-1-4020-5132-6 
024 7 |a 10.1007/1-4020-5132-8  |2 doi 
050 4 |a RC261-271 
072 7 |a MJCL  |2 bicssc 
072 7 |a MED062000  |2 bisacsh 
072 7 |a MJCL  |2 thema 
082 0 4 |a 571.978  |2 23 
082 0 4 |a 616.994  |2 23 
245 1 0 |a Regulation of Carcinogenesis, Angiogenesis and Metastasis by the Proprotein Convertases (PC's)  |h [electronic resource] :  |b A New Potential Strategy in Cancer Therapy /  |c edited by Abdel-Majid Khatib. 
250 |a 1st ed. 2006. 
264 1 |a Dordrecht :  |b Springer Netherlands :  |b Imprint: Springer,  |c 2006. 
300 |a X, 157 p.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
505 0 |a Discovery of the Proprotein Convertases and their Inhibitors -- Signalling Pathways Leading to Furin Expression in Cancer -- PACE4 Gene Expression in Human Ovarian Cancer -- Proprotein Convertases in Tumorigenesis, Angiogenesis and Metastasis -- Proprotein Convertases, Metalloproteases and Tumor Cell Invasion -- Modulation of Integrin Function by Endoproteolytic Processing: Role in Tumour Progression -- Growth Factors: To Cleave or not to Cleave -- Evaluation of Anti-Proprotein Convertase Activity of Diterpene Andrographolid Derived Products. 
520 |a Convertases are widely expressed activating enzymes involved in various physiological and pathological processes. The purpose of this book is to provide detailed and updated information on the role of these molecules in cancer. This book is the first to summarize current knowledge about the importance of protein precursors maturation by the convertases in tumor progression, angiogenesis and metastasis. In each chapter, the importance of the convertases in the activation of various cancer-related molecules including growth factors, adhesion molecules and proteases is discussed. Also this book covers the role of some convertases in the clinical setting. The book will be of interest to basic researchers as well as clinicians. It will also interest those working in the cancer research area and the pharmaceutical industry, who are looking for new strategies in cancer therapy. Finally, this book is also a useful reference for researchers and clinicians pursuing research on growth factors, adhesion molecules, proteases and their implications in the processes of tumor progression, angiogenesis and metastasis. 
650 0 |a Cancer. 
650 0 |a Oncology. 
650 0 |a Chemistry. 
650 1 4 |a Cancer Biology. 
650 2 4 |a Oncology. 
650 2 4 |a Chemistry. 
700 1 |a Khatib, Abdel-Majid.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer Nature eBook 
776 0 8 |i Printed edition:  |z 9789048108640 
776 0 8 |i Printed edition:  |z 9781402047930 
776 0 8 |i Printed edition:  |z 9789401780902 
856 4 0 |u https://doi.uam.elogim.com/10.1007/1-4020-5132-8  |z Texto Completo 
912 |a ZDB-2-SBL 
912 |a ZDB-2-SXB 
950 |a Biomedical and Life Sciences (SpringerNature-11642) 
950 |a Biomedical and Life Sciences (R0) (SpringerNature-43708)