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Radioionidation Reactions for Pharmaceuticals Compendium for Effective Synthesis Strategies /

Molecules of biological interest for in-vivo and in-vitro research or diagnostics of metabolic functions and of neuro-transmission are very often labeled with iodine. Based on state-of-the-art research, this compendium describes the major production routes of the six most relevant iodine radio isoto...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores principales: Coenen, H.H (Autor), Mertens, John (Autor), Mazière, Bernard (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Dordrecht : Springer Netherlands : Imprint: Springer, 2006.
Edición:1st ed. 2006.
Temas:
Acceso en línea:Texto Completo

MARC

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024 7 |a 10.1007/1-4020-4561-1  |2 doi 
050 4 |a QD241-441 
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082 0 4 |a 547  |2 23 
100 1 |a Coenen, H.H.  |e author.  |4 aut  |4 http://id.loc.gov/vocabulary/relators/aut 
245 1 0 |a Radioionidation Reactions for Pharmaceuticals  |h [electronic resource] :  |b Compendium for Effective Synthesis Strategies /  |c by H.H. Coenen, John Mertens, Bernard Mazière. 
246 3 |a With contributions by numerous experts 
250 |a 1st ed. 2006. 
264 1 |a Dordrecht :  |b Springer Netherlands :  |b Imprint: Springer,  |c 2006. 
300 |a XI, 101 p.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
505 0 |a Iodine Radionuclides -- Iodinated Radiopharmaceuticals -- Methods of Radioiodination -- Iodinated Radiopharmaceuticals -- Expert System -- Guidelines for Radioiodination. 
520 |a Molecules of biological interest for in-vivo and in-vitro research or diagnostics of metabolic functions and of neuro-transmission are very often labeled with iodine. Based on state-of-the-art research, this compendium describes the major production routes of the six most relevant iodine radio isotopes and the various methods of labeling molecules of biological, diagnostic or pharmaceutical interest with them. The chapters describe the basic reaction mechanisms, and the influence of iodine introduction on physical/chemical and pharmacological properties. They also include examples of important reaction pathways for the preparation of radio-iodine compounds. The volume is completed by an expert system providing guidelines to obtain the most suitable method of synthesis regarding also cost and time aspects. Worked examples support the novices confronted with radio-iodination reactions. 
650 0 |a Chemistry, Organic. 
650 0 |a Analytical chemistry. 
650 0 |a Physical chemistry. 
650 0 |a Medicinal chemistry. 
650 1 4 |a Organic Chemistry. 
650 2 4 |a Analytical Chemistry. 
650 2 4 |a Physical Chemistry. 
650 2 4 |a Medicinal Chemistry. 
700 1 |a Mertens, John.  |e author.  |4 aut  |4 http://id.loc.gov/vocabulary/relators/aut 
700 1 |a Mazière, Bernard.  |e author.  |4 aut  |4 http://id.loc.gov/vocabulary/relators/aut 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer Nature eBook 
776 0 8 |i Printed edition:  |z 9789048171491 
776 0 8 |i Printed edition:  |z 9789048107698 
776 0 8 |i Printed edition:  |z 9781402045608 
856 4 0 |u https://doi.uam.elogim.com/10.1007/1-4020-4561-1  |z Texto Completo 
912 |a ZDB-2-CMS 
912 |a ZDB-2-SXC 
950 |a Chemistry and Materials Science (SpringerNature-11644) 
950 |a Chemistry and Material Science (R0) (SpringerNature-43709)