Cargando…

Metadata-driven Software Systems in Biomedicine Designing Systems that can adapt to Changing Knowledge /

To build good systems, one needs both good development skills as well as a thorough knowledge of the problem one is trying to solve. Knowledge of software history - what has worked and what hasn't - also helps in these types of detailed projects. Metadata-Driven Software Systems in Biomedicine...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Nadkarni, Prakash M. (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Springer London : Imprint: Springer, 2011.
Edición:1st ed. 2011.
Colección:Health Informatics,
Temas:
Acceso en línea:Texto Completo

MARC

LEADER 00000nam a22000005i 4500
001 978-0-85729-510-1
003 DE-He213
005 20220118090302.0
007 cr nn 008mamaa
008 110527s2011 xxk| s |||| 0|eng d
020 |a 9780857295101  |9 978-0-85729-510-1 
024 7 |a 10.1007/978-0-85729-510-1  |2 doi 
050 4 |a R858-859.7 
072 7 |a MBG  |2 bicssc 
072 7 |a UB  |2 bicssc 
072 7 |a MED000000  |2 bisacsh 
072 7 |a UXT  |2 thema 
082 0 4 |a 610.285  |2 23 
100 1 |a Nadkarni, Prakash M.  |e author.  |4 aut  |4 http://id.loc.gov/vocabulary/relators/aut 
245 1 0 |a Metadata-driven Software Systems in Biomedicine  |h [electronic resource] :  |b Designing Systems that can adapt to Changing Knowledge /  |c by Prakash M. Nadkarni. 
250 |a 1st ed. 2011. 
264 1 |a London :  |b Springer London :  |b Imprint: Springer,  |c 2011. 
300 |a XX, 396 p.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
490 1 |a Health Informatics,  |x 2197-3741 
505 0 |a 1. What is metadata? Types of metadata -- Descriptive (interpreted by humans) -- Technical (utilized by software) -- Some metadata shows characteristics of both -- How metadata is represented -- Why use metadata to build biomedical systems? Caveat: Metadata-driven systems are initially harder to build, Building for change: flexibility and maintainability, Elimination of repetitious coding tasks, Case Study: Table-driven approaches to software design -- 2. Metadata for supporting electronic medical records -- The Entity-Attribute-Value (EAV) data model: -- Why EAV is problematic without metadata-editing capabilities: the TMR experience -- Pros and Cons of EAV: When not to use EAV -- How metadata allows ad hoc query to be data-model agnostic -- Transactional operations vs. warehousing operations -- Case Study: The I2B2 clinical data warehouse model -- Providing end-user customizability, Case Study: EpicCare Flowsheets -- 3. Metadata for clinical study data management systems (CSDMS) -- Critical differences between an EMR and a CSDMS -- Essential elements of a CSDMS -- HTML-based vs. non-Web interfaces: pros and cons -- Case Study: Metadata for robust interactive data validation -- Metadata and the support of basic bioscience research -- Object dictionaries and synonyms: the NCBI Entrez approach -- Fundamentals of object-oriented modeling: the use of classes -- Case study: representing neuroscience data: SenseLab -- Case study: managing phenotype data -- 4. Descriptive Metadata: Controlled Biomedical Terminologies -- Classification of Controlled Vocabularies, with examples: Collections of Terms, Taxonomies: a hierarchical structure, Thesauri: Concepts vs. Terms, Ontologies: Classes and Properties, Cimino's criteria for a good controlled vocabulary, Fundamentals of Description Logics, Pre-coordination vs. compositional approaches to new concept definition, Challenges when the set of permissible operations is incomplete, Difficulties in end-user employment of large vocabularies, The use of vocabulary subsets: the 95/5 problem, Case Study: the SNOMED vocabulary -- 5. Metadata and XML -- Introduction to XML -- Strengths of XML for information interchange -- Misconceptions and common pitfalls in XML use -- Weaknesses of XML as the basis for data modeling -- The Microarray Gene Expression Data (MGED) experience -- Use of the Unified Modeling Language -- UML is intended for human visualization -- UML has an internal XML equivalent (XMI) -- Case Study: Clinical text markup -- 6. Metadata and the modeling of ontologies -- Ontology modeling tools: Protégé -- Common Pitfalls in Ontology Modeling -- Scalable ontology designs -- Supporting reasoning in ontologies: classification -- An introduction to Semantic Web technologies -- Limitations: the open-world assumption -- Case Study: Implementing constraints in SNOMED -- 7. Metadata and Production-Rule Engines -- Introduction to Production-Rule Systems -- Strengths and weaknesses of rule frameworks -- Embedded rule engines -- Data that can be executed as code: the Eval function -- Designing for extensibility -- Supporting versioning -- Case Study: The Jones Criteria for Rheumatic Fever -- 8. Biomedical Metadata Standards -- Why there can be no universal standard: a metadata model is problem-specific -- Standards for Descriptive Metadata -- ISO/IEC 11179: Purpose and Limitations -- Standards for Technical Metadata -- Have been designed for individual problem domains -- CDISC for clinical study data interchange -- Interchange standards for gene expression and proteomics -- 9. The HL7 v3 Reference Information Model -- Elements of the model -- What the model is not intended to encompass -- The clinical document architecture -- The Messaging Standard: Backward Incompatibilities -- Limitations and controversies. 
520 |a To build good systems, one needs both good development skills as well as a thorough knowledge of the problem one is trying to solve. Knowledge of software history - what has worked and what hasn't - also helps in these types of detailed projects. Metadata-Driven Software Systems in Biomedicine lays down some of the foundations and provides a knowledge-base to assist this process. The technical portion of the book consists of database schemas and working code that provide non-trivial examples for the practitioner who is conversant with software development and wishes to employ the approaches described in the book.  Eight of the ten chapters include case studies, while the book also includes extensible designs in biomedical applications: electronic medical records, clinical study data management systems, laboratory research support systems, ontologies, and production-rule subsystems. This book is therefore ideal for individuals who have to interact with large biomedical database systems in an information-technology or informatician capacity, build interfaces to such systems or design new systems themselves. 
650 0 |a Medical informatics. 
650 0 |a Medicine-Research. 
650 0 |a Biology-Research. 
650 0 |a Public health administration. 
650 1 4 |a Health Informatics. 
650 2 4 |a Biomedical Research. 
650 2 4 |a Health Administration. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer Nature eBook 
776 0 8 |i Printed edition:  |z 9780857295095 
776 0 8 |i Printed edition:  |z 9781447126621 
776 0 8 |i Printed edition:  |z 9780857295118 
830 0 |a Health Informatics,  |x 2197-3741 
856 4 0 |u https://doi.uam.elogim.com/10.1007/978-0-85729-510-1  |z Texto Completo 
912 |a ZDB-2-SME 
912 |a ZDB-2-SXM 
950 |a Medicine (SpringerNature-11650) 
950 |a Medicine (R0) (SpringerNature-43714)