Recoding: Expansion of Decoding Rules Enriches Gene Expression

The dynamic nature of decoding the information in messenger RNA was unanticipated at the time the genetic code was first deciphered. We now know that both the meaning of individual codons and the framing of the readout process can be modified by information in specific messenger RNAs. This book desc...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Atkins, John F. (Editor ), Gesteland, Raymond F. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2010.
Edición:1st ed. 2010.
Colección:Nucleic Acids and Molecular Biology, 24
Temas:
Microbiology.
Medical genetics.
Biochemistry.
Cytology.
Medical Genetics.
Cell Biology.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Redefinition
  • Selenocysteine Biosynthesis, Selenoproteins, and Selenoproteomes
  • Reprogramming the Ribosome for Selenoprotein Expression: RNA Elements and Protein Factors
  • Translation of UAG as Pyrrolysine
  • Specification of Standard Amino Acids by Stop Codons
  • Ribosome "Skipping": "Stop-Carry On" or "StopGo" Translation
  • Recoding Therapies for Genetic Diseases
  • Frameshifting - Redirection of Linear Readout
  • Pseudoknot-Dependent Programmed -1 Ribosomal Frameshifting: Structures, Mechanisms and Models
  • Programmed -1 Ribosomal Frameshift in the Human Immunodeficiency Virus of Type 1
  • Ribosomal Frameshifting in Decoding Plant Viral RNAs
  • Programmed Frameshifting in Budding Yeast
  • Recoding in Bacteriophages
  • Programmed Ribosomal ?1 Frameshifting as a Tradition: The Bacterial Transposable Elements of the IS3 Family
  • Autoregulatory Frameshifting in Antizyme Gene Expression Governs Polyamine Levels from Yeast to Mammals
  • Sequences Promoting Recoding Are Singular Genomic Elements
  • Mutants That Affect Recoding
  • The E Site and Its Importance for Improving Accuracy and Preventing Frameshifts
  • Discontiguity
  • Translational Bypassing - Peptidyl-tRNA Re-pairing at Non-overlapping Sites
  • trans-Translation
  • Transcription Slippage
  • Transcript Slippage and Recoding
  • Computational Resources for Studying Recoding.

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