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The Sarcomere and Skeletal Muscle Disease

Although best known for its role in heart disease, the sarcomere--the fundamental unit of muscle contraction--is also involved in skeletal muscle diseases. Chapters in The Sarcomere and Skeletal Muscle Disease provide an up-to-date review of diseases caused by mutated proteins in the different sub-c...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Laing, Nigel G. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2008.
Edición:1st ed. 2008.
Colección:Advances in Experimental Medicine and Biology, 642
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • The Sarcomere and Sarcomerogenesis
  • Skeletal Muscle Alpha-Actin Diseases
  • Nebulin-A Giant Chameleon
  • Skeletal Muscle Disease Due to Mutations in Tropomyosin, Troponin and Cofilin
  • Investigations into the Pathobiology of Thin-Filament Myopathies
  • Mouse Models for Thin Filament Disease
  • Thick Filament Diseases
  • Acute Quadriplegic Myopathy: An Acquired "Myosinopathy"
  • Third Filament Diseases
  • The Z-Disk Diseases
  • Intermediate Filament Diseases: Desminopathy
  • Muscular Integrity-A Matter of Interlinking Distinct Structures via Plectin
  • The Sarcomere and the Nucleus: Functional Links to Hypertrophy, Atrophy and Sarcopenia
  • Other Model Organisms for Sarcomeric Muscle Diseases
  • Therapeutic Approaches for the Sarcomeric Protein Diseases.