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|a 9780387772325
|9 978-0-387-77232-5
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|a 10.1007/978-0-387-77232-5
|2 doi
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|a RC321-580
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|a 612.8
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|a Structural and Functional Organization of the Synapse
|h [electronic resource] /
|c edited by Johannes W. Hell, Michael D. Ehlers.
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|a 1st ed. 2008.
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|a New York, NY :
|b Springer US :
|b Imprint: Springer,
|c 2008.
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|a XVIII, 801 p. 91 illus., 72 illus. in color.
|b online resource.
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|a text
|b txt
|2 rdacontent
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|a computer
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|a online resource
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|a text file
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|a Diversity in Synapse Structure and Composition -- The Role of Glutamate Transporters in Synaptic Transmission -- Structure and Function of Vertebrate and Invertebrate Active Zones -- Neurotransmitter Release Machinery: Components of the Neuronal SNARE Complex and Their Function -- The Molecular Machinery for Synaptic Vesicle Endocytosis -- Initiation and Regulation of Synaptic Transmission by Presynaptic Calcium Channel Signaling Complexes -- Adhesion Molecules at the Synapse -- Dendritic Organelles for Postsynaptic Trafficking -- Structure and Mechanism of Action of AMPA and Kainate Receptors -- Cellular Biology of AMPA Receptor Trafficking and Synaptic Plasticity -- Structure and Function of the NMDA Receptor -- Molecular Properties and Cell Biology of the NMDA Receptor -- Surface Trafficking of Membrane Proteins at Excitatory and Inhibitory Synapses -- Scaffold Proteins in the Postsynaptic Density -- Ca2+ Signaling in Dendritic Spines -- Postsynaptic Targeting of Protein Kinases and Phosphatases -- Long-Term Potentiation -- Homeostatic Synaptic Plasticity -- Ubiquitin and Protein Degradation in Synapse Function -- Signaling from Synapse to Nucleus -- Molecular Organization of the Postsynaptic Membrane at Inhibitory Synapses -- Acid-Sensing Ion Channels (ASICs) and pH in Synapse Physiology -- Glia as Active Participants in the Development and Function of Synapses -- Plasticity of Dentate Granule Cell Mossy Fiber Synapses: A Putative Mechanism of Limbic Epileptogenesis -- Stroke - A Synaptic Perspective -- and Pathological Pain.
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|a Synapses play a central role in the brain by mediating signal transmission between neurons. This book provides a fundamental description of the synapse by leading experts in the field. Each individual synapse carries out its numerous functions in a tiny space, thereby requiring an exquisite molecular and functional arrangement. This book describes the molecular structure and cellular function of central synapses in the brain, providing a detailed view of the brain's fundamental unit of information storage.
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|a Neurosciences.
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|a Neurology .
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|a Neuroscience.
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|a Neurology.
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|a Hell, Johannes W.
|e editor.
|4 edt
|4 http://id.loc.gov/vocabulary/relators/edt
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|a Ehlers, Michael D.
|e editor.
|4 edt
|4 http://id.loc.gov/vocabulary/relators/edt
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|a SpringerLink (Online service)
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|t Springer Nature eBook
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|i Printed edition:
|z 9780387568690
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|i Printed edition:
|z 9780387772318
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|i Printed edition:
|z 9781489979056
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|u https://doi.uam.elogim.com/10.1007/978-0-387-77232-5
|z Texto Completo
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|a ZDB-2-SBL
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|a ZDB-2-SXB
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|a Biomedical and Life Sciences (SpringerNature-11642)
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|a Biomedical and Life Sciences (R0) (SpringerNature-43708)
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