TNF Receptor Associated Factors (TRAFs)

It has been established that TNF receptor associated factors (TRAFs) are critical signaling mediators for not only the TNF receptor superfamily, but also the interleukin-1 receptor/Toll-like receptor superfamily and the T-cell receptors. They play important roles in mammalian biology including embry...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Wu, Hao (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2007.
Edición:1st ed. 2007.
Colección:Advances in Experimental Medicine and Biology, 597
Temas:
Cytology.
Developmental biology.
Data protection.
Cell Biology.
Developmental Biology and Stem Cells.
Data and Information Security.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Phylogeny of the TRAF/MATH Domain
  • TRAF1 and Its Biological Functions
  • Physiological Roles and Mechanisms of Signaling by TRAF2 and TRAF5
  • TRAF3 and Its Biological Function
  • TRAF4, the Unique Family Member
  • Characteristics and Biological Functions of TRAF6
  • Ubiquitination and TRAF signaling
  • Structural Revelations of TRAF2 Function in TNF Receptor Signaling Pathway
  • Protein-Protein Interactions in TRAF3
  • Molecular Basis for the Unique Specificity of TRAF6
  • TRAF Proteins in CD40 Signaling
  • TRAFs in RANK Signaling
  • The LT?R Signaling Pathway
  • LMP1 TRAFficking Activates Growth and Survival pathways
  • Targeting TRAFs for Therapeutic Intervention.

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