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Acute Myelogenous Leukemia Genetics, Biology and Therapy /

Acute myelogenous leukemia (AML), is the most common form of leukemia in adults. AML is a deadly form of malignancy, the prognosis for which has not improved in the last two decades. More importantly, it is a malignancy that is seen in older adults, therefore the number of cases is likely to rise as...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Nagarajan, Lalitha (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2010.
Edición:1st ed. 2010.
Colección:Cancer Treatment and Research, 145
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • The Leukemia Stem Cell
  • Epigenetic Mechanisms in AML - A Target for Therapy
  • Chromosomal Translocations in AML: Detection and Prognostic Significance
  • Chromosomal Deletions in AML
  • Genes Predictive of Outcome and Novel Molecular Classification Schemes in Adult Acute Myeloid Leukemia
  • Receptor Tyrosine Kinase Alterations in AML - Biology and Therapy
  • Lineage-Specific Transcription Factor Aberrations in AML
  • Proleukemic RUNX1 and CBF? Mutations in the Pathogenesis of Acute Leukemia
  • Acute Myeloid Leukemia with Mutated Nucleophosmin (NPM1): Molecular, Pathological, and Clinical Features
  • MicroRNAs: New Players in AML Pathogenesis
  • Murine Models of Human Acute Myeloid Leukemia
  • Apoptosis in Leukemias: Regulation and Therapeutic Targeting
  • Acute Promyelocytic Leukemia: A Paradigm for Differentiation Therapy
  • Immunotherapy of AML
  • Therapy of Acute Myelogenous Leukemia in Adults.