Modulation of Protein Stability in Cancer Therapy

This book contains chapters written by experts in the field of the ubiquitin proteasome system and cancer. The authors have summarized current information on ubiquitin ligases and proteasomes as potential targets for cancer therapy. Topics covered in the book include an overview of ubiquitin ligases...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Sakamoto, Kathleen (Editor ), Rubin, Eric (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2009.
Edición:1st ed. 2009.
Temas:
Cancer.
Medical microbiology.
Medical genetics.
Immunology.
Biochemistry.
Cancer Biology.
Medical Microbiology.
Medical Genetics.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Ubiquitin Ligases and Cancer
  • The 26S Proteasome as a Therapeutic Target in Cancer: Beyond Protease Inhibitors?
  • Targeting HAUSP: Killing Two Birds with One Stone
  • Modulation of Protein Stability: Targeting the VHL Pathway
  • Interrelationship of the Fanconi Anemia/BRCA Pathway
  • Targeting the Sumoylation Pathway
  • Proteasome Inhibitors
  • Targeting Deubiquitinating Enzymes
  • Proteolysis Targeting Chimeric Molecules.

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