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Modulation of Protein Stability in Cancer Therapy
This book contains chapters written by experts in the field of the ubiquitin proteasome system and cancer. The authors have summarized current information on ubiquitin ligases and proteasomes as potential targets for cancer therapy. Topics covered in the book include an overview of ubiquitin ligases...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor Corporativo: | |
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York, NY :
Springer New York : Imprint: Springer,
2009.
|
| Edición: | 1st ed. 2009. |
| Temas: | |
| Acceso en línea: | Texto Completo |
MARC
| LEADER | 00000nam a22000005i 4500 | ||
|---|---|---|---|
| 001 | 978-0-387-69147-3 | ||
| 003 | DE-He213 | ||
| 005 | 20220118181347.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 100301s2009 xxu| s |||| 0|eng d | ||
| 020 | |a 9780387691473 |9 978-0-387-69147-3 | ||
| 024 | 7 | |a 10.1007/978-0-387-69147-3 |2 doi | |
| 050 | 4 | |a RC261-271 | |
| 072 | 7 | |a MJCL |2 bicssc | |
| 072 | 7 | |a MED062000 |2 bisacsh | |
| 072 | 7 | |a MJCL |2 thema | |
| 082 | 0 | 4 | |a 571.978 |2 23 |
| 082 | 0 | 4 | |a 616.994 |2 23 |
| 245 | 1 | 0 | |a Modulation of Protein Stability in Cancer Therapy |h [electronic resource] / |c edited by Kathleen Sakamoto, Eric Rubin. |
| 250 | |a 1st ed. 2009. | ||
| 264 | 1 | |a New York, NY : |b Springer New York : |b Imprint: Springer, |c 2009. | |
| 300 | |a X, 165 p. 35 illus. |b online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file |b PDF |2 rda | ||
| 505 | 0 | |a Ubiquitin Ligases and Cancer -- The 26S Proteasome as a Therapeutic Target in Cancer: Beyond Protease Inhibitors? -- Targeting HAUSP: Killing Two Birds with One Stone -- Modulation of Protein Stability: Targeting the VHL Pathway -- Interrelationship of the Fanconi Anemia/BRCA Pathway -- Targeting the Sumoylation Pathway -- Proteasome Inhibitors -- Targeting Deubiquitinating Enzymes -- Proteolysis Targeting Chimeric Molecules. | |
| 520 | |a This book contains chapters written by experts in the field of the ubiquitin proteasome system and cancer. The authors have summarized current information on ubiquitin ligases and proteasomes as potential targets for cancer therapy. Topics covered in the book include an overview of ubiquitin ligases, deubiquitinating enzymes, and the proteasome. Specific diseases resulting from deregulated ubiquitin ligases, such as Von-Hippel-Lindau disease and Fanconi anemia are also discussed. Finally, novel approaches and drugs to target proteins involved in sumoylation, ubiquitination, and degradation are described. | ||
| 650 | 0 | |a Cancer. | |
| 650 | 0 | |a Medical microbiology. | |
| 650 | 0 | |a Medical genetics. | |
| 650 | 0 | |a Immunology. | |
| 650 | 0 | |a Biochemistry. | |
| 650 | 1 | 4 | |a Cancer Biology. |
| 650 | 2 | 4 | |a Medical Microbiology. |
| 650 | 2 | 4 | |a Medical Genetics. |
| 650 | 2 | 4 | |a Immunology. |
| 650 | 2 | 4 | |a Biochemistry. |
| 700 | 1 | |a Sakamoto, Kathleen. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 700 | 1 | |a Rubin, Eric. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 710 | 2 | |a SpringerLink (Online service) | |
| 773 | 0 | |t Springer Nature eBook | |
| 776 | 0 | 8 | |i Printed edition: |z 9781441924018 |
| 776 | 0 | 8 | |i Printed edition: |z 9780387565002 |
| 776 | 0 | 8 | |i Printed edition: |z 9780387691435 |
| 856 | 4 | 0 | |u https://doi.uam.elogim.com/10.1007/978-0-387-69147-3 |z Texto Completo |
| 912 | |a ZDB-2-SBL | ||
| 912 | |a ZDB-2-SXB | ||
| 950 | |a Biomedical and Life Sciences (SpringerNature-11642) | ||
| 950 | |a Biomedical and Life Sciences (R0) (SpringerNature-43708) | ||