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Multiple Testing Procedures with Applications to Genomics
This book establishes the theoretical foundations of a general methodology for multiple hypothesis testing and discusses its software implementation in R and SAS. The methods are applied to a range of testing problems in biomedical and genomic research, including the identification of differentially...
| Clasificación: | Libro Electrónico |
|---|---|
| Autores principales: | , |
| Autor Corporativo: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York, NY :
Springer New York : Imprint: Springer,
2008.
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| Edición: | 1st ed. 2008. |
| Colección: | Springer Series in Statistics,
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| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- Multiple Hypothesis Testing
- Test Statistics Null Distribution
- Overview of Multiple Testing Procedures
- Single-Step Multiple Testing Procedures for Controlling General Type I Error Rates, ?(Fvn)
- Step-Down Multiple Testing Procedures for Controlling the Family-Wise Error Rate
- Augmentation Multiple Testing Procedures for Controlling Generalized Tail Probability Error Rates
- Resampling-Based Empirical Bayes multiple Testing Procedures for Controlling Generalized Tail Probability Error Rates
- Simulation Studies: Assessment of Test Statistics Null Distributions
- Identification of Differentially Expressed and Co-Expressed Genes in High-Throughput Gene Expression Experiments
- Multiple Tests of Association with Biological Annotation Metadata
- HIV-1 Sequence Variation and Viral Replication Capacity
- Genetic Mapping of Complex Human Traits Using Single Nucleotide Polymorphisms: The ObeLinks Project
- Software Implementation.