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Sigma Receptors Chemistry, Cell Biology and Clinical Implications /
Sigma receptors are promising drug development targets for a host of neurological, psychiatric, oncological, immunological, cardiovascular, ophthalmological, and gastrointestinal disorders. They are structurally unique proteins that are distinct from classical G protein-coupled receptors, ionotropic...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor Corporativo: | |
| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York, NY :
Springer US : Imprint: Springer,
2007.
|
| Edición: | 1st ed. 2007. |
| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- ? Receptors: Historical Perspective and Background
- Medicinal Chemistry: New Chemical Classes and Subtype-Selective Ligands
- Irreversible ? Compounds
- Pharmacophore Models for ?1 Receptor Binding
- Cloning of ?1 Receptor and Structural Analysis of Its Gene and Promoter Region
- Site-Directed Mutagenesis
- ? Receptor Modulation of Ion Channels
- Subcellular Localization and Interacellular Dynamics of ?1 Receptors
- Intracellular Signaling and Synaptic Plasticity
- Modulation of Classical Neurotransmitter Systems by ? Receptors
- ?2 Receptors: Regulation of Cell Growth and Implications for Cancer Diagnosis and Therapeutics
- Cognitive Effects of ? Receptor Ligands
- ? Receptors and Scizophrenia
- Potential Role of ? Ligands and Neurosteroids in Major Depression
- ? Receptors and Drug Abuse
- ?1 Receptors and the Modulation of Opiate Analgesics
- ? Receptors in the Immune System: Implications for Potential Therapeutic Intervention - An Overview
- ? Receptors and Gastrointestinal Function.