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Selenium Its Molecular Biology and Role in Human Health /

Selenium is an essential trace element in the diet of humans and many other life forms. As discussed in this book, selenium plays an important role in preventing certain forms of cancer, heart disease and other cardiovascular and muscle disorders. Evidence points to numerous other health benefits in...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Hatfield, Dolph L. (Editor ), Berry, Marla J. (Editor ), Gladyshev, Vadim N. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer US : Imprint: Springer, 2006.
Edición:2nd ed. 2006.
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Selenium: A historical perspective
  • Selenium: A historical perspective
  • Biosynthesis of selenocysteine and its incorporation into protein
  • Selenium metabolism in prokaryotes
  • Mammalian and other eukaryotic selenocysteine tRNAs
  • Evolution of selenocysteine decoding and the key role of selenophosphate synthetase in the pathway of selenium utilization
  • SECIS RNAs and K-turn binding proteins. A survey of evolutionary conserved RNA and protein motifs
  • SECIS binding proteins and eukaryotic selenoprotein synthesis
  • The importance of subcellular localization of SBP2 and EFsec for selenoprotein synthesis
  • Selenocysteine biosynthesis and incorporation may require supramolecular complexes
  • Selenium-containing proteins
  • Selenoproteins and selenoproteomes
  • Deletion of selenoprotein P gene in the mouse
  • Selenium and methionine sulfoxide reduction
  • Selenoprotein W in development and oxidative stress
  • The 15-kDa selenoprotein (Sep15): functional analysis and role in cancer
  • Regulation of glutathione peroxidase-1 expression
  • Selenoproteins of the glutathione system
  • New roles of glutathione peroxidase-1 in oxidative stress and diabetes
  • Selenoproteins of the thioredoxin system
  • Mitochondrial and cytosolic thioredoxin reductase knockout mice
  • Selenium, deiodinases and endocrine function
  • Biotechnology of selenocysteine
  • Selenium and human health
  • Selenium, selenoproteins and brain function
  • Selenium as a cancer preventive agent
  • Peering down the kaleidoscope of thiol proteomics and unfolded protein response in studying the anticancer action of selenium
  • Genetic variation among selenoprotein genes and cancer
  • Selenium and viral infections
  • Role of selenium in HIV/AIDS
  • Effects of selenium on immunity and aging
  • Selenium and male reproduction
  • Mouse models for assessing the role of selenoproteins in health and development
  • Drosophila as a tool for studying selenium metabolism and role of selenoproteins
  • Selenoproteins in parasites
  • Incorporating 'omics' approaches to elucidate the role of selenium and selenoproteins in cancer prevention
  • Selenium-induced apoptosis
  • Selenoprotein mimics
  • Update of human dietary standards for selenium.