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Dose Finding in Drug Development
When you go to the pharmacy and fill a prescription, have you ever wondered if the dose of the medication is right for you? Can the dose be too low so that the drug will not work? Can the dose be too high that it may cause some potential problem? How do people learn about dosing information? This bo...
| Clasificación: | Libro Electrónico |
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| Autor Corporativo: | |
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York, NY :
Springer New York : Imprint: Springer,
2006.
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| Edición: | 1st ed. 2006. |
| Colección: | Statistics for Biology and Health,
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| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- and New Drug Development Process
- Dose Finding Based on Preclinical Studies
- Dose-Finding Studies in Phase I and Estimation of Maximally Tolerated Dose
- Dose-Finding in Oncology-Nonparametric Methods
- Dose Finding in Oncology-Parametric Methods
- Dose Response: Pharmacokinetic-Pharmacodynamic Approach
- General Considerations in Dose-Response Study Designs
- Clinical Trial Simulation-A Case Study Incorporating Efficacy and Tolerability Dose Response
- Analysis of Dose-Response Studies-Emax Model
- Analysis of Dose-Response Studies-Modeling Approaches
- Multiple Comparison Procedures in Dose Response Studies
- Partitioning Tests in Dose-Response Studies with Binary Outcomes
- Analysis of Dose-Response Relationship Based on Categorical Outcomes
- Power and Sample Size for Dose Response Studies.