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Peptide Nucleic Acids, Morpholinos and Related Antisense Biomolecules

This volume is unique to the existing literature in the Peptide Nucleic Acid field, in that it focuses on comparing and contrasting PNA with other available oligonucleotide homologues and considers areas in which these biomolecules could be profitably applied to clinical and diagnostic applications....

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores principales: Janson, Christopher (Autor), During, Matthew (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer US : Imprint: Springer, 2006.
Edición:1st ed. 2006.
Colección:Medical Intelligence Unit
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Research Applications
  • The Many Faces of PNA
  • Modulation of Nucleic Acid Information Processing by PNAs
  • Targeted Gene Delivery
  • Imaging Gene Expression in the Brain with Peptide Nucleic Acid (PNA) Antisense Radiopharmaceuticals and Drug Targeting Technology
  • Receptor-Specific Targeting with Complementary Peptide Nucleic Acids Conjugated to Peptide Analogs and Radionuclides
  • Morpholinos and PNAs Compared
  • Chemistry of Locked Nucleic Acids (LNA)
  • Recent Applications of RNA Interference (RNAi) in Mammalian Systems
  • Clinical Applications
  • Peptide Nucleic Acids as Epigenetic Inhibitors of HIV-1
  • Therapeutic Uses of Peptide Nucleic Acids (PNA) in Oncology
  • PNAs as Novel Cancer Therapeutics
  • Medicinal Chemistry of Plasmid DNA with Peptide Nucleic Acids
  • Locked Nucleic Acids (LNA) and Medical Applications
  • Peptide Nucleic Acids as Agents to Modify Target Gene Expression and Function
  • Peptide Nucleic Acids
  • The Use of PNAs and Their Derivatives in Mitochondrial Gene Therapy
  • Gene Silencing through RNA Interference
  • Transcriptional Activation of Human CREB Gene Promoter Using Bis-PNA (Peptide Nucleic Acid).